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A Meta-Analysis Of Neuromyelitis Optica Epidemiology In Latin American Nations, Brittany M. Zengotita
A Meta-Analysis Of Neuromyelitis Optica Epidemiology In Latin American Nations, Brittany M. Zengotita
Honors Undergraduate Theses
Neuromyelitis Optica (NMO) is a rare, autoimmune, neurodegenerative disease selectively affecting the optic nerves and spinal cord. Relapsing NMO is nine times more prevalent in women than in men and approximately one-quarter of NMO patients have symptoms of another autoimmune disorder (National Institute of Health, 2019). NMO has not been linked to any genetic mutations and the cause of the disorder is unknown beyond the general understanding that the body produces anti-aquaporin-4 antibodies (AQP4) which mistakenly attack cells in the nervous system. NMO affects roughly one percent of that of Multiple Sclerosis (4000-8000 patients total) in the United States, but …