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Full-Text Articles in Medicine and Health Sciences
Advancing Rna Virus Discovery And Biology With Whole Genome Sequencing, Mariah Katherine Taylor
Advancing Rna Virus Discovery And Biology With Whole Genome Sequencing, Mariah Katherine Taylor
Theses and Dissertations (ETD)
Two RNA virus families that pose a threat to human and animal health are Hantaviridae and Coronaviridae. These RNA viruses which originate in wildlife continue and will continue to cause disease, and hence, it is critical that scientific research define the mechanisms as to how these viruses spillover and adapt to new hosts to become endemic. One gap in our ability to define these mechanisms is the lack of whole genome sequences for many of these viruses. To address this specific gap, I developed a versatile amplicon-based whole-genome sequencing (WGS) approach to identify viral genomes of hantaviruses and severe acute …
Poster: Sars-Cov-2 Neuroinvasion, Heather M. Tatusko
Poster: Sars-Cov-2 Neuroinvasion, Heather M. Tatusko
Nursing Student Class Projects (Formerly MSN)
Over the last century, science and literature has reported neurological manifestations during various disease outbreaks as well as long-term sequelae following epidemics and pandemics. Some of the first neurological symptoms reported with Coronavirus Disease 2019 (COVID-19; caused by severe acute respiratory syndrome coronavirus 2 [SARS-Cov-2]) were anosmia and dysgeusia, suggesting SARS-CoV-2 penetrance of the central nervous system (CNS). To date, the definite clinical and pathological basis of CNS involvement of SARS-CoV-2 remains poorly understood, with the neurovirulence of SARS-CoV-2 and its neuroinvasive potential remaining largely unknown. The author’s poster will explore neurological manifestations of COVID-19 disease, the direct and indirect …