Medicine and Health Sciences Commons^™

Effect Of Monounsaturated Fat Rich Almonds On Hemostatic And Inflammatory Factors In Healthy Adults, Kristianne M. Connell

Loma Linda University Electronic Theses, Dissertations & Projects

Background: The frequent consumption of nuts is inversely associated with the incidence of cardiovascular disease. Nuts are known to decrease the risk of cardiovascular disease by reducing serum total and low-density lipoprotein (LDL) cholesterol. Markers of inflammation including C-reactive protein, E-selectin and interleukin-6 have been proposed to be newer risk factors for cardiovascular disease. However, the influence of nuts such as almonds on markers of inflammation and hemostasis that influence cardiovascular disease risk is not currently known.

Objective: The objective of this study was to determine the effect of almond consumption on markers of inflammation and hemostatic factors in healthy …

Breathlessness Descriptors In Patients With Chronic Obstructive Pulmonary Disease Versus Congestive Heart Failure, Adelaide De Souza Caroci

Loma Linda University Electronic Theses, Dissertations & Projects

This cross-sectional descriptive study investigated breathlessness (dyspnea) in stable patients with Chronic Obstructive Pulmonary Disease (COPD) and Congestive Heart Failure (CHF). The purpose of this study was (a) to characterize the most common terms COPD and CHF patients use to describe their breathing, (b) to identify the frequency of dyspnea in patients with COPD and CHF, and (c) to determine the intensity of dyspnea in these populations.

A purposive sample of 60 patients, 30 with moderate to severe COPD and 30 patients with moderate to severe CHF, met the inclusion criteria and were enrolled in this study. The participants provided …

Effects Of Liposome-Encapsulated Tnf-Alpha And Radiation Against Colon Cancer, Dong Won Kim

Loma Linda University Electronic Theses, Dissertations & Projects

Previous studies have shown that tumor necrosis factor-α (TNF-α) can augment the antitumor effects of radiation, inhibiting tumor progression to a greater extent than either modality alone. However, nonspecific toxicities associated with TNF-α have limited its use as an adjuvant. This limitation is potentially resolved with the encapsulation of TNF-α in sterically stabilized, PEGylated liposomes (STEALTH®). Thus, the overall hypothesis of the research was that the combination of radiation with STEALTH® liposome encapsulated TNF-α (SL-TNF-α) will have greater efficacy and fewer dose-limiting side effects in the LS174T human colorectal tumor xenograft model compared to the combination of free TNF-α and …

Using The Polymerase Chain Reaction To Determine The Prevalence Of Lyme Disease Bacteria, Borrelia Burgdorferi, In Ixodes Pacificus Ticks From San Bernardino County In Southern California, Richard Allen

Theses Digitization Project

The purpose of this study was to determine the prevalence of Lyme Disease (LD) bacteria in adult Ixodes pacificus ticks collected from the mountains of San Bernardino County in Southern California. Seven hundred fifty four I. pacificus adults were collected from the Pacific Crest Trail and adjacent areas. The Polymerase Chain Reaction (PCR) was used to screen ticks for Borrelia burgdorferi infection by targeting two different DNA loci. Oligonucleotide primers targeting both the ospA and fla genes were used in the assay. Ticks were processed in pools of three, and genomic DNA from the ticks was extracted with a commercial …

Mycobacteriosis In Striped Bass, Morone Saxatilis, From Virginia Waters Of Chesapeake Bay, Jennifer L. Cardinal

Dissertations, Theses, and Masters Projects

No abstract provided.

Combating An Elusive Enemy: Understanding Autism, Brandy Ussery

Honors Theses

Autism is a disorder that affects one out of every one thousand children. It occurs more frequently in boys than in girls and brings with it complications that deprive those affected of a nom1al life. One such individual is a boy named Tyler Kubinski. Tyler is a twelve-year-old severely autistic child from Paragould, Arkansas. Tyler's world is limited by his inability to speak or communicate further than a scream or contorted laugh. He does not frighten or agitate easily but will strike out fiercely with his muscular legs or well-aimed spit to anyone nearby. Tyler does not interact with his …

Calcium Metabolism Of Bone In Microgravity: An Investigation And Simulation Of Bone Demineralization In Space, Benjamin Peacock

Honors Theses

Extended space exploration poses many physiological problems that must be overcome before humanity can reach past the boundaries of Earth's orbit. The farthest a human has been able to travel is to the moon and back, and currently astronauts are confined to orbiting the Earth. While many astronauts and cosmonauts have remained aboard the space station Mir for months, their stay was not without detrimental effects upon their return. Currently, the International Space Station and missions to Mars are the projects involving humans in space at the National Aeronautics and Space Administration (NASA).

In this experiment, a ground-based simulation utilizing …

Living With Hepatitis C : A Literature Review, & The Physical, Psychological And Social Impacts Of Hepatitis C And The Effects On Quality Of Life, Narelle Cockman

Theses : Honours

Hepatitis C (HCV) is a blood borne virus that affects the liver. It has become one of the most widespread blood borne viruses in Australia, now reaching epidemic proportions within the population. Given that HCV is a chronic long-term illness, with long term effects, a positive diagnosis potentially impacts on various aspects of' a person's life. The aim of this paper was to review HCV related research to examine what it is like for people living with the virus and the possible personal and social impacts of a positive diagnosis. The nature of HCV, including current incidence and prevalence rates, …

An Assessment Of Prothrombotic Tendency In Humans Using Functional And Genomic Determinants In The South Eastern Irish Population, Carmel Cullen

Theses

Venous thrombosis occurs in about 1 per 1,000 individuals per year. It is a serious disorder and accounts for a significant number of hospital admissions and deaths annually. Thrombophilia describes the familial or acquired disorders of the haemostatic mechanism that predispose to thrombosis. Inherited thrombophilia can be defined as a genetically determined tendency to venous thromboembolism Mutations in genes that code for proteins involved directly (or indirectly) In blood coagulation have been associated with prothrombotic status. Laboratory investigations for thrombophilia include screening for deficiencies of antithrombin, protein C or protein S and testing for activated protein C resistance. Together these …