Medicine and Health Sciences Commons^™

Oral Lichen Planus : A Clinical Study Of The Association With Diabetes Mellitus And Vascular Hypertension, Gordon M. Rick

Loma Linda University Electronic Theses, Dissertations & Projects

This investigation concerns the relationship of diabetes mellitus and vascular hypertension to oral lichen planus. Questionnaires were sent to 470 patients with oral lichen planus: 286 responded. Of these patients 103 were examined clinically, and 74 with current lesions were divided into ''keratotic'' and ''erosive'' categories. These patients underwent three-hour oral glucose tolerance tests; also, their asterial blood pressure was determined. In the survey group, diabetes was reported about three times more frequently by those with "erosive"; oral lichen planus than by those ''keratoic" lesions. The overall prevalence of diabetes was about two and one-half times greater than expected compared …

Microscopic Evaluation Of Topically Applied Chlorhexidine Gluconate On Gingival Wound Healing In Dogs, Robert C. Hirst

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to evaluate microscopically the effect of topically applied 2% chlorhexidine gluconate on the healing of gingival wounds in dogs.

One week after the teeth were scaled and polished, seven experimental wound sites were prepared in the facial gingiva adjacent to the four premolars on each side of the maxillary arch in six young Labrador dogs. From this point the dogs were fed a soft plaque-inducing diet. Chlorhexidine solution was applied daily to either the right or left maxillary premolars while on the opposite side of the arch in three dogs the first and second …

Studies On The Regulation Of Cell Growth And Contact Inhibition Using Concanavalin A And Dibutyryl Adenosine Cyclic Monophosphate, Robert W. Teel

Loma Linda University Electronic Theses, Dissertations & Projects

Both dibutyryl cyclic AMP and trypsinized concanavalin A have been shown to inhibit growth in certain cell lines but little testing of these substances has been done using human tumor cell lines. Further, there are at this time no published experimental attempts to correlate the effects on growth with a particular phase of the cell cycle in any cell line.

My experimental data show that the human tumor cell lines HeLa, HEp 2 and KB exhibit pronounced inhibition of growth when treated with trypsinized concanavalin A and reach a contact-inhibited state at a density far below that to which these …