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The Effects Of 24r, 25-Dihydroxyvitamin D3 And 24s, 25-Dihydroxyvitamin D3 On Phosphate Transport In Vivo, Yu Meng
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
This research studied the effects of the two isomers of 24,25(OH)2D3 on phosphate absorption in vivo to increase our understanding of the effects of 24,25(OH)2D3 on phosphate transport in vivo, and its two isomers. The current work demonstrates that 24R,25(OH)2D3 is capable of decreasing phosphate absorption after a 1h injection in vivo and 24S,25(OH)2D3 can increase phosphate absorption after a 5h injection, but this stimulation disappears at time points after 5h.
Since 24,25(OH)2D3 is made in vitamin D-replete animals, the observation that 24R,25(OH)2D …