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Potential Role Of Dietary Nitrate In Relation To Cardiovascular And Cerebrovascular Health, Cognition, Cognitive Decline And Dementia: A Review, Anjana Rajendra, Nicola P. Bondonno, Stephanie R. Rainey-Smith, Samantha L. Gardener, Jonathan M. Hodgson, Catherine P. Bondonno

Research outputs 2022 to 2026

There is currently no effective treatment for dementia, of which Alzheimer's disease (AD) is the most common form. It is, therefore, imperative to focus on evidence-based preventive strategies to combat this extremely debilitating chronic disease. Nitric oxide (NO) is a key signalling molecule in the cardiovascular, cerebrovascular, and central nervous systems. Vegetables rich in nitrate, such as spinach and beetroot, are an important source of NO, with beneficial effects on validated markers of cardiovascular health and an association with a lower risk of cardiovascular disease. Given the link between cardiovascular disease risk factors and dementia, together with the important role …