Medicine and Health Sciences Commons^™

Evaluating Dimensional Accuracy And Reliability Of "Stitched" Small Field Of View (Ssfov) Cone Beam Computed Tomography (Cbct) Datasets For Use In Proprietary Dental Implant Guided Surgery Software, Nicholas Luke Egbert

Theses and Dissertations (ETD)

Background: Recently a "stitched" small field of view (SSFOV) cone beam computed tomography (CBCT) extraoral imaging system (Kodak 9000D, Carestream Health Inc, Kodak Dental Systems, Marne‑la‑Vallee, France) has been released. The benefits of the 3D stitching module of stitched SFOV CBCT may include: broader range of applications, affordability, flexibility, safety optimizing radiation dose and improved workflow. With the reduced effective dose of radiation and cost to both the patient and clinician, this superior imaging modality becomes more accessible to the community, potentially elevating the standard of care. Currently, stitched data sets are restricted to diagnostic data gathering only. To date, …

Eccentric Interchangeability Of The Semi‑Adjustable Articulator: A Pilot Study, Mark James Hopkins

Theses and Dissertations (ETD)

Background: Dental articulation is a method of approximating the patient's mandibular motion in order to allow for analysis of dental relations and fabrication of appliances. The most prevalent method used in teaching institutions is the semi-adjustable articulator. Several of these instruments claim interchangeability without loss of clinical accuracy and studies have supported this claim. No studies to date have assessed the interchangeability of the articulators in any relation other than hinge axis closure. Assessment of the accuracy of interchangeability of calibrated articulators will inform the profession of this parameter of articulation and allow for informed decisions on whether or not …

Efficacy Of Temporary Fixed Retention Following Comprehensive Orthodontic Treatment, Mark J. Owens

Theses and Dissertations (ETD)

Instability of the occlusion is a common problem following orthodontic treatment. The purpose of the present research was to evaluate posttreatment relapse at long-term recall (> 10 years) in cases (A) treated with temporary fixed mandibular retention plus Hawley retainers compared to (B) a similar group retained with just removable retention (standard Hawley type retainers alone). Fixed retainers were removed after having been in place for about 2.5 years. Following this period, use of removable retention was left up to the discretion of the patient in both groups. Data consisted of orthodontic records of 166 American whites, all of whom …

Activity Of Epithelial Defensin Hbd-3 Against A Periodontal Pathogen, Norman B. Fine

Theses and Dissertations (ETD)

Defensins are cationic (positive-charged) peptides with broad-spectrum antibiotic activity. In humans, there are two types of defensins, alpha (α) and beta (β). Human neutrophils contain four α-defensins known as Human Neutrophil Peptide (HNP) 1-4. Epithelial cells produce four β-defensins known as Human Beta Defensin (HBD) 1-4. Gram-negative anaerobic bacteria that are associated with periodontal disease are resistant to human α-defensins, but are killed by β-defensins.

HBD-3 is the most active β-defensin. HBD-3 is a longer peptide than HNP 1-4. HBD-3 has additional amino acid residues with hydrophobic side chains near the N-terminus and residues with cationic side chains at the …

The Long-Term Stability Of Class Ii Cases Treated In A Private Practice Using A Straightwire Appliance: A Dental Cast Analysis, Lina K. Kulkarni

Theses and Dissertations (ETD)

Achieving long-term stability after orthodontic treatment is a major challenge for orthodontists. The previous literature shows that relapse occurs at a considerable magnitude. The purpose of the present study was to determine the amount and type of long-term, posttreatment relapse that occurs in a homogeneous group of patients treated by a single experienced orthodontist in a private practice setting. Dental casts from a sample of 30 Class II division 1 Caucasian females treated without extractions were evaluated at pretreatment (mean age = 13.1 years), posttreatment (mean age = 15.9 years) and recall (mean age = 28.3 years) to determine the …

Craniofacial Changes Following Nonextraction Orthodontic Treatment: A Long-Term Cephalometric Analysis, James Austin Rahaim

Theses and Dissertations (ETD)

Long-term posttreatment cephalometric changes from late adolescence into early adulthood were analyzed in this study. Lateral cephalometric radiographs from a sample of 30 Class II division 1 Caucasian females treated without extractions were evaluated at posttreatment (mean age = 15.9 years) and recall (mean age = 28.3 years). All of the subjects were treated in the private practice of a single, experienced practitioner. The cephalograms were examined to investigate changes in the cranial base, midface, maxilla, mandible, maxillomandibular relationships, dental relationships, and the soft tissue profile that occurred at an average of 12.4 years posttreatment. Descriptive and inferential statistics were …

Inhibition Of Monocyte Chemotaxis And Chemokine Macrophage Inflammatory Protein-1 Alpha, And Interleukin-8 Secretion By Lipopolysaccharide Isolated From Periodontal Pathogens, Andrew Karl Gray

Theses and Dissertations (ETD)

The vast majority of periodontal pathogens are classified as gram negative bacteria. These bacteria have an outermost membrane consisting of lipopolysaccharide (LPS), a molecule that can act as an endotoxin and elicit an immune response. The lipopolysaccharide structure consists of three major regions: oligosaccharide, core, and lipid A. Oligosaccharide is exposed on the cell surface, and lipid A anchors LPS in the outer membrane. LPS has been known to hinder certain defensive mechanisms of the immune system by secreting products that interfere with signals that promote chemotaxis of leukocytes enabling the pathogens to go unrestricted. When LPS binds to the …