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Full-Text Articles in Medicine and Health Sciences
A Review On The Biodistribution, Pharmacokinetics And Toxicity Of Bismuth-Based Nanomaterials, Samireh Badrigilan, Fatemeh Heydarpanahi, Jalal Choupani, Mehdi Jaymand, Hadi Samadian, Mojtaba Hoseini-Ghahfarokhi, Thomas J. Webster, Lobat Tayebi
A Review On The Biodistribution, Pharmacokinetics And Toxicity Of Bismuth-Based Nanomaterials, Samireh Badrigilan, Fatemeh Heydarpanahi, Jalal Choupani, Mehdi Jaymand, Hadi Samadian, Mojtaba Hoseini-Ghahfarokhi, Thomas J. Webster, Lobat Tayebi
School of Dentistry Faculty Research and Publications
Here, bismuth-based nanomaterials (Bi-based NMs) are introduced as promising theranostic agents to enhance image contrast as well as for the therapeutic gain for numerous diseases. However, understanding the interaction of such novel developed nanoparticles (NPs) within a biological environment is a requisite for the translation of any promising agent from the lab bench to the clinic. This interaction delineates the fate of NPs after circulation in the body. In an ideal setting, a nano-based therapeutic agent should be eliminated via the renal clearance pathway, meanwhile it should have specific targeting to a diseased organ to reach an effective dose and …
Manufacturing And Characterization Of Mechanical, Biological And Dielectric Properties Of Hydroxyapatite-Barium Titanate Nanocomposite Scaffolds, Mina Tavangar, Fatemeh Heidari, Raziye Hayati, Fahimeh Tabatabaei, Daryoosh Vashaee, Lobat Tayebi
Manufacturing And Characterization Of Mechanical, Biological And Dielectric Properties Of Hydroxyapatite-Barium Titanate Nanocomposite Scaffolds, Mina Tavangar, Fatemeh Heidari, Raziye Hayati, Fahimeh Tabatabaei, Daryoosh Vashaee, Lobat Tayebi
School of Dentistry Faculty Research and Publications
In this research, hydroxyapatite (HA)-based ceramics were produced as suitable ceramic implants for orthopedic applications. To improve the physical, mechanical, electrical and biological properties of pure HA, we developed composite scaffolds of HA-barium titanate (BT) by cold isostatic pressing and sintering. Microstructure, crystal phases, and molecular structure were analyzed by using scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR), respectively. Bulk density values were measured using the Archimedes method. The effect of different percentages of BT on cell proliferation, viability, and ALP activity of dental pulp stem cells (DPSCs) was assessed …
Structure, Wettability, Corrosion And Biocompatibility Of Nitinol Treated By Alkaline Hydrothermal And Hydrophobic Functionalization For Cardiovascular Applications, S. Rahimipour, E. Salahinejad, E. Sharifi, H. Nosrati, Lobat Tayebi
Structure, Wettability, Corrosion And Biocompatibility Of Nitinol Treated By Alkaline Hydrothermal And Hydrophobic Functionalization For Cardiovascular Applications, S. Rahimipour, E. Salahinejad, E. Sharifi, H. Nosrati, Lobat Tayebi
School of Dentistry Faculty Research and Publications
The main objective of this study is to hydrophobize nitinol (Ni-Ti alloy) for cardiovascular applications. For this purpose, medical nitinol samples were subjected to sodium hydroxide hydrothermal treatments at various temperatures, followed by hexadecyltrimethoxysilane (HDTMS) functionalization. Then, the structure, wettability, corrosion, cytocompatibility and cell adhesion of the prepared samples were evaluated. According to the results, porous blade-shaped layers of sodium titanate were formed on the substrate surface as a result of the alkaline treatment. These nano-rough features offered considerable hydrophobicity after HDTMS processing, where a maximum water contact angle of about 140° was obtained for the sample treated at 120 …