Medicine and Health Sciences Commons^™

Effects Of Fluoride On Precipitation And Hydrolysis Of Octacalcium Phosphate In An Experimental Model Simulating Enamel Mineralization During Amelogenesis, M. J. Mura-Galelli, H. Narusawa, T. Shimada, M. Iijima, T. Aoba

Cells and Materials

The present study was undertaken to investigate effects of fluoride at low concentrations on the precipitation of calcium phosphates on hydroxyapatite seeds in media resembling the enamel fluid composition. To this end, we used a new crystal growth model adopting a miniaturized reaction column. Experimental solutions had the composition similar to that found in the enamel fluid, except for calcium concentrations which were adjusted at 1.0 and 0.5 mM. Precipitation reactions taking place in the system at the higher supersaturation ([Ca] = 1 mM) were characterized by co-precipitation of platelike OCP and rod-like apatite crystals, while the reaction at the …