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Role Of Expression Ki-67 In Diagnosis Of Oral Cancer, Amani Mohamed, Osama El-Shall, Naglaa El-Kilani
Role Of Expression Ki-67 In Diagnosis Of Oral Cancer, Amani Mohamed, Osama El-Shall, Naglaa El-Kilani
Al-Azhar Journal of Dentistry
Purpose: The study was designed to assess the effect of Ki-67 on oral squamous cell carcinoma (OSCC) with the correlation of biomarker level and grades of OSCC. Material and methods: 26 samples (life biopsies) were inspected in this study, 20 of them are OSCC and 6 are normal. The specimens were processed by the routine histological procedure to prepare them for histopathological and immuno-histochemical examinations. Antibodies expression with anti-Ki-67 antibody was evaluated using image analysis for area percentage with the Leica Q550 image analyzer computer system. Statistical analysis was performed using ANOVA test. Results: Histopathological examination of oral squamous cell …