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Faculty of Dental Medicine (Girls' branch)
BM-MSCs; Submandibular salivary glands; Radiation; immunofluorescence; anti- α- amylase 1
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Stem Cells And Their Potential Effect On Irradiated Submandibular Salivary Glands In Mice, Seham Hallool, Mona Farid, Samah Mehanny, Hanan Abdel Hamid
Stem Cells And Their Potential Effect On Irradiated Submandibular Salivary Glands In Mice, Seham Hallool, Mona Farid, Samah Mehanny, Hanan Abdel Hamid
Al-Azhar Journal of Dentistry
Purpose: the objective of the present study was to evaluate the effect of BM-MSCs on irradiated submandibular salivary glands in mice and to determine at which stage post-irradiation the cells should be transplanted. Materials and methods: 58 adult male mice were used, 10 for preparation of PKH-26-labeled BM-MSCs and the remaining 48 mice were divided into: control group (GӀ) consisted of 6 mice without radiation and experimental groups consisted of 42 irradiated mice irradiated with a single dose of 15Gy. They were randomly divided into three groups: GӀӀ (+ve control): 18 irradiated not treated mice and two treated groups each …