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Osteoblast And Chondrocyte Specific Contribution Of The Runx2 Gene During The Development Of Cleidocranial Dysplasisa, Kayla Renee King
Osteoblast And Chondrocyte Specific Contribution Of The Runx2 Gene During The Development Of Cleidocranial Dysplasisa, Kayla Renee King
All ETDs from UAB
The Runx2 transcription factor is essential for the differentiation of mesenchymal stem cells into functional chondrocytes and osteoblasts. In humans, the haploinsufficiency of the Runx2 gene is associated with cleidocranial dysplasia (CCD). The CCD is characterized by short stature, open sutures and fontanels in the skull, hypoplastic clavicles and supernumerary teeth. Skeletal elements disrupted in CCD patients are developed by intramembranous and/or endochondral ossification. However, the cell type specific roles of the Runx2 gene in the development of CCD-associated skeletal defects remain unknown. The main goal of this research was to define the specific role of the Runx2 gene in …
Volumetric Analysis Of The Lips In Aging African American And Caucasian Males, Matthew Steven Leftwich
Volumetric Analysis Of The Lips In Aging African American And Caucasian Males, Matthew Steven Leftwich
All ETDs from UAB
VOLUMETRIC ANALYSIS OF THE LIPS IN AGING AFRICAN AMERICAN AND CAUCASIAN MALES DEPARTMENT OF ORTHODONTICS ABSTRACT The purpose of this cross sectional study was to analyze the volumetric changes in lip volume with respect to aging in a population of African American and Caucasian males using three-dimensional imaging technology. Materials and Methods: A sample size of 102 Caucasian males and 90 African American males with balanced faces divided into five age groups distributed as follows:[20-30], [31-40], [41-50], [51-60], [61-70[.Three-dimensional images were obtained using the 3dMDfaceTM camera system. The subjects were placed in front of the camera in natural head position …