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Medicine and Health Sciences Commons

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Dentistry

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ALL - Honors Theses

2024

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Genus-Specific Probes And Advanced Imaging Technologies For Bacterial Detection In Canine Dental Plaque, Meghan Stern May 2024

Genus-Specific Probes And Advanced Imaging Technologies For Bacterial Detection In Canine Dental Plaque, Meghan Stern

ALL - Honors Theses

Periodontal disease is an inflammation of the gums that can progress to bone resorption in the jaw and eventual tooth loss. A contributor to this disease is the buildup of subgingival and supragingival plaque, which consists of hundreds of bacterial species. To study the bacteria involved in periodontal disease, we use extracted canine teeth as our model. Canines were chosen based on their similarities with humans at the bacterial phylum level, as well as having a similar progression of periodontal disease. However, there are significant differences at lower levels of taxonomy of bacterial abundance and prevalence. The abundance and prevalence …