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Full-Text Articles in Medicine and Health Sciences
Satisfaction Among Early And Mid-Career Dentists In A Metropolitan Dental Hospital In China, Xiaoxi Cui, David G. Dunning, Na An
Satisfaction Among Early And Mid-Career Dentists In A Metropolitan Dental Hospital In China, Xiaoxi Cui, David G. Dunning, Na An
Journal Articles: College of Dentistry
A growing body of research has examined career satisfaction among dentists using a standardized instrument, dentist satisfaction survey (DSS). This project examined career satisfaction of early to mid-career dentists in China, a population whose career satisfaction, heretofore, has not been studied. This is an especially critical time to examine career satisfaction because of health care reform measures being implemented in China. A culturally sensitive Chinese-language version of the DSS (CDSS) was developed and electronically administered to 367 early and mid-career dentists in a tertiary dental hospital in Beijing, China. One hundred and seventy respondents completed the survey. The average total …
S4s8-Rpa Phosphorylation As An Indicator Of Cancer Progression In Oral Squamous Cell Carcinomas., Jeff Rector, Sasha Kapil, Kelly J. Treude, Phyllis Kumm, Jason G. Glanzer, Brendan M. Byrne, Shengqin Liu, Lynette M. Smith, Dominick J. Dimaio, Peter J. Giannini, Russell B. Smith, Greg G. Oakley
S4s8-Rpa Phosphorylation As An Indicator Of Cancer Progression In Oral Squamous Cell Carcinomas., Jeff Rector, Sasha Kapil, Kelly J. Treude, Phyllis Kumm, Jason G. Glanzer, Brendan M. Byrne, Shengqin Liu, Lynette M. Smith, Dominick J. Dimaio, Peter J. Giannini, Russell B. Smith, Greg G. Oakley
Journal Articles: College of Dentistry
Oral cancers are easily accessible compared to many other cancers. Nevertheless, oral cancer is often diagnosed late, resulting in a poor prognosis. Most oral cancers are squamous cell carcinomas that predominantly develop from cell hyperplasias and dysplasias. DNA damage is induced in these tissues directly or indirectly in response to oncogene-induced deregulation of cellular proliferation. Consequently, a DNA Damage response (DDR) and a cell cycle checkpoint is activated. As dysplasia transitions to cancer, proteins involved in DNA damage and checkpoint signaling are mutated or silenced decreasing cell death while increasing genomic instability and allowing continued tumor progression. Hyperphosphorylation of Replication …