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Articles 1 - 6 of 6
Full-Text Articles in Medicine and Health Sciences
Identification And Characterization Of Microrna Differentially Expressed In Macrophages Exposed To Porphyromonas Gingivalis Infection, Olivier Huck, J Al-Hashemi, L Poidevin, O Poch, J Davideau, H Tenenbaum, Salomon Amar
Identification And Characterization Of Microrna Differentially Expressed In Macrophages Exposed To Porphyromonas Gingivalis Infection, Olivier Huck, J Al-Hashemi, L Poidevin, O Poch, J Davideau, H Tenenbaum, Salomon Amar
NYMC Faculty Publications
MicroRNAs (miRNAs) are short, noncoding RNAs involved in the regulation of several processes associated with inflammatory diseases and infection. Bacterial infection modulates miRNA expression to subvert any innate immune response. In this study we analyzed, using microarray analysis, the bacterial modulation of miRNAs in bone marrow-derived macrophages (BMMs) in which activity was induced by infection with Porphyromonas gingivalis The expression of several miRNAs was modulated 3 h postinfection (at a multiplicity of infection of 25). A bioinformatic analysis was performed to further identify pathways related to the innate immune host response under the influence of selected miRNAs. To assess the …
The Effects Of Sports Drinks On Teeth, Gabriel Kaye
The Effects Of Sports Drinks On Teeth, Gabriel Kaye
The Science Journal of the Lander College of Arts and Sciences
With a push towards a more active lifestyle, the sports drink industry has grown substantially in recent years. However, despite their popularity, sports drinks contain acid, giving them extremely low pHs, which can cause erosion. There have been many studies, including self-administered surveys, studies in vitro, and studies in situ that have shown sports energy drinks cause dental erosion, leading to permanent loss of tooth volume and a softening of the outer layer of the tooth.
Is Tooth Bleaching Really Safe?, Yehoshua Krasnow
Is Tooth Bleaching Really Safe?, Yehoshua Krasnow
The Science Journal of the Lander College of Arts and Sciences
The field of cosmetic dentistry emerged when people began to realize the importance of a good smile. Stains on teeth were no longer deemed acceptable with the advent of cheap and safe procedures like tooth bleaching. This new procedure replaced the older, more costly and invasive method of laminated veneers and crowns. The chemistry behind this bleaching occurs via unstable hydroxyl radicals and thus the question arose as to how safe this accepted procedure really is. The purpose of this paper is to analyze the negative ramifications of tooth bleaching and to determine if it’s truly safe. The null hypothesis …
Using Dental Stem Cells To Regenerate Tooth Tissue And Whole Tooth Replacement, Peretz Rapoport
Using Dental Stem Cells To Regenerate Tooth Tissue And Whole Tooth Replacement, Peretz Rapoport
The Science Journal of the Lander College of Arts and Sciences
Irreversible dental problems such as dental carries and periodontal disease create a plethora of general and oral health issues. Although there are solutions to treat these different problems, an emphasis has been placed on finding a solution to these points with the help of bioengineering and stem cells. Using stem cells to treat these problems could result in a more permanent fix than the methods dentists employ now. Two novel approaches to fixing irreversible dental problems via stem cell therapy are tooth tissue regeneration and whole tooth replacement. This paper reviews the advantages and disadvantages of using dental pulp stem …
The Relationship Between Periodontitis And Cardiovascular Disease, Jonathan Krupka
The Relationship Between Periodontitis And Cardiovascular Disease, Jonathan Krupka
The Science Journal of the Lander College of Arts and Sciences
The relationship between periodontal disease and cardiovascular disease has been the subject of much research in recent years. The aim of this study is to review and analyze the relevant literature regarding this relationship, with an emphasis on determining a presence of periodontal bacteria from the periodontal pocket in atheromatous plaques, and to explore the biological role of inflammatory mechanisms that may link periodontitis and cardiovascular disease. Although there seems to be conflicting reports, the overall consensus confirms the presence of periodontal bacteria, such as Porphyromonas gingivalis, in atheromatous plaques. Additionally, the presence of systemic markers of cardiovascular disease in …
Oral Health: The Need For Both Conventional Microbial And Molecular Characterization, Elisheva Friedman, Negin Alizadeh, Zvi G. Loewy
Oral Health: The Need For Both Conventional Microbial And Molecular Characterization, Elisheva Friedman, Negin Alizadeh, Zvi G. Loewy
Touro College of Pharmacy (New York) Publications and Research
This study aims to consider the microbial distribution in oral disease, as well as gene analysis and expression, in elucidating: 1, the fundamental underpinnings of oral disease, and 2, the potential relationship between oral diseases and systemic health. A key focus is identifying the microbiota associated with oral disease manifestations characterized by both conventional microbiological and molecular methods. Variations in the observed microbial populations characterized by conventional and molecular approaches have been identified for caries, periodontitis, peri-implantitis, and stomatitis. The discovery of therapeutic approaches for oral disease will require comprehensive microbial and genomic analysis. This study evaluated the current state …