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Full-Text Articles in Medicine and Health Sciences

Sepsis Pathophysiology, Samantha Kingsley Aug 2020

Sepsis Pathophysiology, Samantha Kingsley

Nursing Student Class Projects (Formerly MSN)

Sepsis is one of the most common diagnoses in medical intensive care units (MICUs) worldwide. Sepsis is a medical emergency where prompt intervention is vital to promoting positive patient outcomes. Septic shock develops when sepsis has progressed to the point of persistent hypotension despite appropriate fluid resuscitation. It is important to recognize the early signs of sepsis and intervene to prevent further progression. As the understanding of the pathophysiology has developed further over the years, the treatments and outcomes associated with sepsis have also improved. However, prompt recognition and intervention have always been at the forefront of management and should …


Malignant Hyperthermia, Kathryn Hernandez Jul 2020

Malignant Hyperthermia, Kathryn Hernandez

Nursing Student Class Projects (Formerly MSN)

Malignant hyperthermia (MH) is a condition in which the body goes into a hypermetabolic state affecting skeletal muscle in response to receiving inhaled anesthetics or the neuromuscular blocking agent, succinylcholine. MH is an autosomal dominant disorder that is most closely related to a defect in the ryanodine receptor. The defective receptor causes a rapid increase of intracellular calcium causing hyperthermia, tachycardia, tachypnea, hypercapnia, increased oxygen consumption, acidosis, hyperkalemia, muscle rigidity, and rhabdomyolysis. With the complexity of this disorder and its unique pathophysiological process it is crucial that all parts of the surgical team, especially anesthesia providers, understand how to treat …


Pulmonary Arterial Hypertension, Gifty Menka Jul 2020

Pulmonary Arterial Hypertension, Gifty Menka

Nursing Student Class Projects (Formerly MSN)

Pulmonary arterial hypertension (PAH), is diagnosed as persistently elevated pressures in the pulmonary arteries. It is a severe disease that requires early diagnosis and treatment as it can be life-threatening if not treated promptly and adequately. The initial presenting signs and symptoms such as lethargy, malaise, and exercise intolerance can be vague, making it difficult to diagnose. Also, doctors at centers that specialize in treating PAH are the only ones who can properly diagnose the condition and initiate disease-targeted therapy. There are different types of PAH; the World Health Organization (WHO) recognizes 5 groups of pulmonary hypertension (PH), and they …


Coarctation Of The Aorta, Megan Berens Jul 2020

Coarctation Of The Aorta, Megan Berens

Nursing Student Class Projects (Formerly MSN)

Coarctation of the aorta (CoA) is a ductal dependent congenital heart defect that causes decreased blood flow to areas of the body distal to the site of constriction. CoA is one of the most common congenital heart defects, though is often missed in neonatal assessments. Neonatal patients with CoA often present to the hospital in a state of cardiopulmonary collapse. CoA is occasionally diagnosed in older children and adults who have upper extremity hypertension and decreased femoral pulses. CoA repair is performed through surgery or percutaneous catheter interventions. Patients with CoA have an increased likelihood of developing other vascular lesions. …


Acute Kidney Injury, Mary Boadu Jul 2020

Acute Kidney Injury, Mary Boadu

Nursing Student Class Projects (Formerly MSN)

This poster presents up to date information regarding acute kidney injury (AKI) which often presents in patients in the intensive care unit (ICU). Most patients may not have identifiable symptoms therefore, advanced practice clinicians are charged with a great responsibility to diagnose, treat and follow-up with such patients. It is pertinent that clinicians recognize AKI early in an effort to prevent adverse consequences as seen in the progression of AKI to chronic kidney disease (CKD).


Chronic Thromboembolic Pulmonary Hypertension, Alyssa Curry Jul 2020

Chronic Thromboembolic Pulmonary Hypertension, Alyssa Curry

Nursing Student Class Projects (Formerly MSN)

Chronic pulmonary hypertension (CTEPH) is a rare and underdiagnosed complication of unresolved acute pulmonary embolism (PE). A chronic fibrotic thrombus replaces the unresolved emboli in the pulmonary vascular bed causing pre-capillary pulmonary hypertension (Mahmud et al., 2018). Symptoms rang from mild nonspecific such as exercise intolerance and dyspnea. As the disease progresses, symptoms present similarly to right ventricular heart failure (Gopalan et al., 2016). Although the pathophysiology and etiology of CTEPH is still not fully understood, risk factors include increased size of the PE, right ventricular strain, chronic inflammation, and defects in fibrinolysis among others (Fernandes et al., 2016). Treatment …


Aortic Stenosis, Christina Lower Jul 2020

Aortic Stenosis, Christina Lower

Nursing Student Class Projects (Formerly MSN)

Aortic Stenosis is the progressive and permanent narrowing of the aortic valve that is located between the left ventricle and the aorta. The pathophysiology is endothelial damage to the valve resulting in lipid penetration, calcific changesand valve stiffness.Major risk factors for aortic stenosis are natural aging>60 years(atherosclerotic changes in vasculature) and male gender.In the early phases of aortic stenosis, the body compensatesvia hypertrophy of the left ventricle to accommodateforthe increased pressure gradient. Progression is typically over years to decades untildecreased outflow of blood leads toinadequate perfusion to major organsystems including the heart itself. Patientsdo not typically have symptoms until …


Hyperosmolar Hyperglycemic State, Justin Momeyer Jul 2020

Hyperosmolar Hyperglycemic State, Justin Momeyer

Nursing Student Class Projects (Formerly MSN)

Hyperosmolar hyperglycemic state (HHS) and diabetic ketoacidosis (DKA) are dangerous complications of diabetes. HHS is examined in this poster and compared to DKA. Even though both have some similarities, they have very different laboratory profiles, patient presentations, treatments, complications, and can require different levels of care. With diabetes becoming more common amongst patients in the hospital, it is imperative that healthcare providers are aware of both of these complications. Nurses who understand both of these complications are able to act pro-actively for their patients, ask questions regarding correct treatments and orders, include the right providers in the care team, and …