Medicine and Health Sciences Commons^™

Phr: Patient Health Record, Quinn Nelson

Theses/Capstones/Creative Projects

The rapid development of information technology systems has expanded into multiple disciplines and results in systems that are limited by initial design and implementation: the Healthcare Information Technology (HIT) space is no different. The introduction of the Electronic Health Record (EHR) system has changed the way healthcare operates. Initial designs of these systems were focused on serving the needs of insurance companies and healthcare billing departments. Research shows that the design of EHR systems negatively impact provider-patient interactions and the care they receive. This capstone project capitalizes on the collaboration efforts between UNO and UNMC – by joining a research …

Project Renew Worcester, Danni Yue, Amy Zhang, Jing Han, Omid Ashrafi, Yiming Xu

School of Professional Studies

n The client for this capstone project is RENEW Worcester which is a fledgling solar power project whose main goals are to bring renewable energy in the form of solar power into local, primarily low-income communities and are committed to the mission of making the transition off of fossil fuels to clean, renewable power. Based in Worcester, Massachusetts, they are a local chapter of Co-op Power which is a consumer-owned sustainable energy cooperative (co-op) made up of numerous different local chapters all over the New England area as well as the state of New York. The problem that we will …

Cleaver: Classification Of Everyday Activities Via Ensemble Recognizers, Samantha Hsu

Master's Theses

Physical activity can have immediate and long-term benefits on health and reduce the risk for chronic diseases. Valid measures of physical activity are needed in order to improve our understanding of the exact relationship between physical activity and health. Activity monitors have become a standard for measuring physical activity; accelerometers in particular are widely used in research and consumer products because they are objective, inexpensive, and practical. Previous studies have experimented with different monitor placements and classification methods. However, the majority of these methods were developed using data collected in controlled, laboratory-based settings, which is not reliably representative of real …

Emotion Recognition Using Deep Convolutional Neural Network With Large Scale Physiological Data, Astha Sharma

USF Tampa Graduate Theses and Dissertations

Classification of emotions plays a very important role in affective computing and has real-world applications in fields as diverse as entertainment, medical, defense, retail, and education. These applications include video games, virtual reality, pain recognition, lie detection, classification of Autistic Spectrum Disorder (ASD), analysis of stress levels, and determining attention levels. This vast range of applications motivated us to study automatic emotion recognition which can be done by using facial expression, speech, and physiological data.

A person’s physiological signals such are heart rate, and blood pressure are deeply linked with their emotional states and can be used to identify a …

A Characterization Of The Medical-Legal Partnership (Mlp) Of Nebraska Medicine, Jordan Pieper

Capstone Experience

This research study was completed at Legal Aid of Nebraska’s Health, Education, and Law Project through the partnership it has formed working with Nebraska Medicine and Iowa Legal Aid. Traditionally, health and disease have always been viewed exclusively as "healthcare" issues. But with healthcare consistently growing towards holistic approaches to help patients, we now know there are deeper, structural conditions of society that can act as strong driving forces of a person's poor daily living conditions that can negatively impact health. The importance of a Medical-Legal Partnership is that it considers a patient's social determinants of health (SDHs). The goal …

Network Analysis Of Scientific Collaboration And Co-Authorship Of The Trifecta Of Malaria, Tuberculosis And Hiv/Aids In Benin., Gbedegnon Roseric Azondekon

Theses and Dissertations

Despite the international mobilization and increase in research funding, Malaria, Tuberculosis and HIV/AIDS are three infectious diseases that have claimed more lives in sub Saharan Africa than any other place in the World. Consortia, research network and research centers both in Africa and around the world team up in a multidisciplinary and transdisciplinary approach to boost efforts to curb these diseases. Despite the progress in research, very little is known about the dynamics of research collaboration in the fight of these Infectious Diseases in Africa resulting in a lack of information on the relationship between African research collaborators. This dissertation …

Evaluation Of Drug-Loaded Gold Nanoparticle Cytotoxicity As A Function Of Tumor Tissue Heterogeneity., Hunter Allan Miller

Electronic Theses and Dissertations

The inherent heterogeneity of tumor tissue presents a major challenge to nanoparticle-medicated drug delivery. This heterogeneity spans from the molecular to the cellular (cell types) and to the tissue (vasculature, extra-cellular matrix) scales. Here we employ computational modeling to evaluate therapeutic response as a function of vascular-induced tumor tissue heterogeneity. Using data with three-layered gold nanoparticles loaded with cisplatin, nanotherapy is simulated with different levels of tissue heterogeneity, and the treatment response is measured in terms of tumor regression. The results show that tumor vascular density non-trivially influences the nanoparticle uptake and washout, and the associated tissue response. The drug …

Bayesian Analytical Approaches For Metabolomics : A Novel Method For Molecular Structure-Informed Metabolite Interaction Modeling, A Novel Diagnostic Model For Differentiating Myocardial Infarction Type, And Approaches For Compound Identification Given Mass Spectrometry Data., Patrick J. Trainor

Electronic Theses and Dissertations

Metabolomics, the study of small molecules in biological systems, has enjoyed great success in enabling researchers to examine disease-associated metabolic dysregulation and has been utilized for the discovery biomarkers of disease and phenotypic states. In spite of recent technological advances in the analytical platforms utilized in metabolomics and the proliferation of tools for the analysis of metabolomics data, significant challenges in metabolomics data analyses remain. In this dissertation, we present three of these challenges and Bayesian methodological solutions for each. In the first part we develop a new methodology to serve a basis for making higher order inferences in metabolomics, …

Is Information Systems Misuse Always Bad? A New Perspective On Is Misuse In Hospitals Under The Context Of Disasters, Dheyaaldin Alsalman

Masters Theses & Doctoral Dissertations

Although the extant literature has investigated how individuals engage in inappropriate behaviors based on the rational choice theory (RCT) (e.g., computer misconduct), the neutralization theory (e.g., IS security policies violation), and workarounds under normal situations, it has given little consideration to how individuals are involved in misuse of information systems with a good intention under the context of disasters. To fill this research gap, we propose a selfless misuse model, which offers a theoretical explanation for the concept of individuals’ selfless misuse intention under uncertainty caused by disasters. In this study, we show why employees make decisions to misuse the …

Inference And Analysis Of Multilayered Mirna-Mediated Networks In Cancer, Duc Do

Dissertations (1934 -)

MicroRNAs (miRNAs) are small noncoding transcripts that can regulate gene expression, thereby controlling diverse biological processes. Aberrant disruptions of miRNA expression and their interactions with other biological agents (e.g., coding and noncoding transcripts) have been associated with several types of cancer. The goal of this dissertation is to use multidimensional genomic data to model two different gene regulation mechanisms by miRNAs in cancer. This dissertation results from two research projects. The first project investigates a miRNA-mediated gene regulation mechanism called competing endogenous RNA (ceRNA) interactions, which suggests that some transcripts can indirectly regulate one another's activity through their interactions with …

Life Can Change In The Blink Of An Eye Capstone, Christopher Rutigliano, Jillian Elalaoui, Kristin Humphrey, Phillip Gates, Mohamed Ndjikam, Highness Meena, Adam Menard, Spencer Pickney

School of Professional Studies

Texting and driving is one of the most widespread and uncontrollable of epidemics that have arose to prominence in the 21st century. Texting and driving is now a global issue, that has left nations across the road scrambling to implement new laws and preventative measures to stunt the increasing rates of accidents and fatalities caused by texting and driving. The severity of the issue has lead to a multitude of different entities ranging from domestic and foreign governments, cell phone and car manufacturers, cell phone carriers, and insurance agencies to seek new methods to prevent texting and driving. Determining the …

A Guide For Hiring Mature Employees At Ascentria, Binghe Change, Calleigh Leach, Elsie Lu, Hongquiang You, Mengge Wang, Nina Mariotti

School of Professional Studies

This paper will explore existing literature on aspects of an intergenerational workplace in a nonprofit organization and provide recommendations for recruiting and retaining older employees for a human service organization, Ascentria Care Alliance, in Worcester, MA. The paper will review research on trends in the nonprofit industry, a comprehensive breakdown of generational workplace values, reasons people are returning to work and effective marketing strategies that appeal to older generations. Marketing strategies specifically will explore best practices for website design, social media usage, and job descriptions. Additionally, this paper will research case studies of nonprofits with successful intergenerational workforce initiatives, as …

Leicester Research A Study In Effective Technology In Education, Jimeshkumar Chauhan, Anna Lakomy, Li Liu, Christina Mccarthy, Scott Mccarthy, Roman Pena, Emilie Smiley

School of Professional Studies

The LPS Research Team has been tasked with researching and recommending a technology plan for a new school that Leicester Public Schools is planning to build. In this paper, we present an overview of the our goals and our client’s goals, an introduction to industry trends, and discuss our findings based on research conducted via interviews with schools that have undergone similar projects. We also outline the conclusions drawn from this research and our analysis of the data we uncovered, and make specific recommendations for technology to be utilized in Leicester’s new school. Finally, we present a 3-part framework that …

My Choice Greens, Alina Zulfikarova, Amelia Mohr, Hesi Zhang, Ruiqi Huang, Sean Tatar, Yuhao Zhou, Zijun Zhou

School of Professional Studies

My Choice Programs for Independent Living is a nonprofit in Worcester, Massachusetts that helps individuals with special needs. In 2016, My Choice Programs added a branch to their organization called My Choice Greens. My Choice Greens is committed to growing fresh produce in their hydroponic farm. The profit generated from selling their vegetables is put back into direct programming for My Choice Programs. My Choice Greens is the first hydroponic farm in Worcester, but unfortunately not many people are aware of their program. Also, since they are a small nonprofit, they do not have sufficient funding or resources to market …

Optical Heritage Museum: An Interactive Touch, Connor Guerin, Ankur Halwai, Jinzhao Liu, Qi Liu, Yangjing Wang, Yashaswini Bharti

School of Professional Studies

Optical Heritage Museum (OHM) was established in 1983 with the aim to preserve, promote and display historical artifacts of the optics industry and educate all of its vital role optics has played in societal development. Over the years, the museum has grown in its physical space along with exhibit development to engage audiences in innovative, effective methods. Clark University’s School of Professional Studies department and curator of Optical Heritage Museum, Mr. Whitney’s Whitney, have establish a collaboration that has spanned over two semesters with the goal to support and aid in improving OHM. Our capstone group was assigned the task …

Leicester Public Schools Information And Data Portal: Research And Recommendations, Yue Cen, Natalie Bonetti, Rashida Buchanan, Sathark Jain, Yuwei Wong

School of Professional Studies

The purpose of this project is to develop a strategy for the creation of a multifaceted portal to help with the organization and dissemination of information about the Leicester public school district. The functionality of this portal is to provide comparative financial, demographic, and academic data to other relative school districts in the area, both for the parents’ and for the city’s reference. It will be an examination into the best practices for creating a portal, both technological and aesthetic recommendations, as well as research into the value the publication of this data would provide for the parents of current …

Water In Worcester A Campaign For Public Fluoridation, Ryan Early, Xiao Gu, Yajing Huang, Lauren Meininger, Emma Phillips, Yao Su

School of Professional Studies

Water in Worcester: A Campaign for Public Fluoridation arose as a project from our sponsors, Chris Philbin, Vice President of Government Relations at UMass Memorial Health Care, and Joe O’Brien, former Worcester Mayor, Executive Director of the Environmental League of Massachusetts, and Clark University Adjunct Professor. Our goal has been to produce resources that will support the fight for fluoridation in the City of Worcester. Fluoridation has failed to pass in Worcester on four separate occasions, but Mr. Philbin and Mr. O’Brien believe that the time has come to try again.

In order to fluoridate Worcester’s water supply, the municipal …

Epoca House: The Implementation Strategy, Courtney Thomas, Yaffa Fain, Shuxiao Teng, Mingjun Xie

School of Professional Studies

This capstone report provides a written strategic implementation plan for EPOCA House. EPOCA, Ex-Prisoners and Prisoners Organizing for Community Advancement, is a non-profit dedicated to creating better resources and opportunities for prisoners and ex-prisoners in Worcester. The organization’s most recent initiative, EPOCA House, is a transitional facility that will provide reentry services and temporary housing to ex-offenders in and around the Worcester area. Recently, Massachusetts passed a comprehensive criminal justice reform bill that will dramatically reduce the number of people being incarcerated; however, little attention is focused on what will happen to individuals after they leave prison. At the same …

Canine For Disabled Kids Awareness Campaign Research And Implementation Plan, Jiamin Gu, Kendall Harcourt, Chang Liu, Kiamu Liu, Jemmie Tejada

School of Professional Studies

According to the Americans with Disabilities Act (ADA) service animals are: “dogs that are individually trained to do work or perform tasks for people with disabilities” ( ADA, 2015). On the other hand, emotional support animals are: “dogs that provide comfort and support in forms of affection and companionship for an individual suffering from various mental and emotional conditions.” In addition, an emotional support animal is not required to perform any specific tasks for a disability like service dogs are (Ibid).

The ADA limits the number of questions that can be asked to protect the privacy of utilizers. In fact, …

Adult Learners: A Targeted Marketing Approach, Sarah Baldelli, Camilo Botero, Camille Ferreol, Caleb Horton, Xinyue Ma, Stefan Sprinkmoller

School of Professional Studies

The development of the Adult Learner Capstone Project started with a focus and need to learn more about affinity groups in the Worcester area in order to reach the potential adult learner demographic. Although some partnerships already existed, the Director of Marketing and Communications for Graduate Admissions, Tara Probeck, yearned to explore the potential partnerships and alternative uses of professional organizations to market to the current working professionals. From this idea, our capstone project was introduced in hopes of establishing a comprehensive and exhaustive list of potential organizational partnerships, specific for the School of Professional Studies.

Inbound Marketing, Hasini Assiriyage, Isabelle Zoeckler, Emmanuel Aghado, Kefu Bu, Xiouyu Jiang, Rajesh Kamble, Yan Wang

School of Professional Studies

This study looks into inbound marketing practice through the process of secondary research. This insight on best practices and market examples have been employed in order to identify the benefits of Inbound Marketing for the School of Professional Studies at Clark University. Through the research, this team has consolidated a number of recommendations for the SPS marketing strategies moving forward. A focus has been placed on identifying solutions, which were effective and financially feasible. The primary solutions are internally sourced; with a future long term recommendation of seeking advice from a third party firm to automate the process.

A Social Media Plan For The Changemakers’ Playground, Meng Cong, Ciara Kilian, Xinling Wang, Sumanth Wilson, Chenyu Yan

School of Professional Studies

The purpose of this project was to create a social media plan for the Changemakers’ Playground campaign. The Changemakers’ Playground is a website thought up by our client, Sarah Lange, whereby ordinary individuals doing extraordinary things in their community can be celebrated for the work they are doing. Each person featured on the website, also known as a Changemaker, was interviewed by Sarah and that interview was split into three videos to be posted on the Changemakers’ Playground website throughout the week they are being featured. In short, our task was to create the Facebook, Twitter, and Instagram content to …

Clear The Air: Moving Towards A More Supportive, Welcoming, Tobacco-Free Clark University, Edward Aroko, Simon Elliot, Jackson Espe, Donovan Smith, Michael Spanos

School of Professional Studies

The deleterious health effects of the consumption of tobacco products, especially for youth, have been documented thoroughly and are nearly universally recognized. Numerous federal, state, and local regulations, coupled with health education and tobacco cessation initiatives have been launched to address these effects. Although these pushes have done much to reduce the rates of preventable health conditions and death due to the usage of tobacco, there remains much work to be done at the local level to discourage and disrupt patterns of substance use and abuse. The mission of Clark Clear the Air is to propose various and creative ways …

Quantitative Phenotype Analysis To Identify, Validate And Compare Rat Disease Models, Yiqing Zhao

Theses and Dissertations

Introduction

The laboratory rat has been widely used as an animal model in biomedical research. There are many strains exhibiting a wide variety of phenotypes. Capturing these phenotypes in a centralized database provides researchers with an easy method for choosing the appropriate strains for their studies. Current resources such as NBRP and PhysGen provided some preliminary work in rat phenotype databases. However, there are drawbacks in both projects: (1) small number of animals (6 rats) used by NBRP; (2) NBRP project is a one-time effort for each strain; (3) PhysGen web interface only enables queries within a single study – …

Designing Interactive Virtual Environments With Feedback In Health Applications., Yi Li

Electronic Theses and Dissertations

One of the most important factors to influence user experience in human-computer interaction is the user emotional reaction. Interactive environments including serious games that are responsive to user emotions improve their effectiveness and user satisfactions. Testing and training for user emotional competence is meaningful in healthcare field, which has motivated us to analyze immersive affective games using emotional feedbacks. In this dissertation, a systematic model of designing interactive environment is presented, which consists of three essential modules: affect modeling, affect recognition, and affect control. In order to collect data for analysis and construct these modules, a series of experiments were …

Computational Modelling Of Human Transcriptional Regulation By An Information Theory-Based Approach, Ruipeng Lu

Electronic Thesis and Dissertation Repository

ChIP-seq experiments can identify the genome-wide binding site motifs of a transcription factor (TF) and determine its sequence specificity. Multiple algorithms were developed to derive TF binding site (TFBS) motifs from ChIP-seq data, including the entropy minimization-based Bipad that can derive both contiguous and bipartite motifs. Prior studies applying these algorithms to ChIP-seq data only analyzed a small number of top peaks with the highest signal strengths, biasing their resultant position weight matrices (PWMs) towards consensus-like, strong binding sites; nor did they derive bipartite motifs, disabling the accurate modelling of binding behavior of dimeric TFs.

This thesis presents a novel …

Cross-Platform Openhds Web Application, Nick Littlefield

Thinking Matters Symposium Archive

A proof of concept cross platform data collection application for Demographic and Health studies has been developed. This application allows for the collection of information about locations, individuals, births, and deaths within a region. This application can be run on both mobile devices, laptops, and desktops.

Compressed Sensing For Few-View Multi-Pinhole Spect With Applications To Preclinical Imaging, Benjamin Michael Rizzo

Dissertations (1934 -)

Single Photon Emission Computed Tomography (SPECT) can be used to identify and quantify changes in molecular and cellular targets involved in disease. A radiopharmaceutical that targets a specific metabolic function is administered to a subject and planar projections are formed by imaging emissions at different view angles around the subject. The reconstruction task is to determine the distribution of radioactivity within the subject from the projections. We present a reconstruction approach that utilizes only a few view angles, resulting in a highly underdetermined system, which could be used for dynamic imaging applications designed to quantify physiologic processes altered with disease. …

Audubon Data Project Final Report, Askhat Beygenov, Valinur Kutlambetov, Shrikant Patel, Phoebe Roberts, Ulfat Sayyed, Shriram Sivaraman

School of Professional Studies

The Audubon Data Project was initiated as a Clark University Capstone project. The project’s client, Mass Audubon’s Shaping the Future of Your Community program, had identified a need to improve their data management methods and make better use of their data. The Capstone team, composed of Clark University graduate students, met with the client regularly to review the current state of the data and potential improvements to be made. The process began with a data review. During the review we worked with the client to explicitly define the purposes and requirements of the data, the current process for updating and …

Worcester Center For Crafts: A Transition To Online Sales, Monica Gow, Carly Branconnier, Srilatha Prodduturi, Ekaterina Shusharina, Alberta Yamoah

School of Professional Studies

The Clark University School of Professional Studies created a capstone team consisting of Monica Gow, Carly Branconnier, Iana Matkovskaia, Srilatha Prodduturi, Ekaterina Shusharina, and Alberta Yamoah to assist Worcester Center for Crafts (WCC) with the launch of their new online store. Worcester Center for Crafts wanted to showcase their beautiful American handmade crafts on an online platform, Shopify, in order to increase their sales and expand their market reach. The capstone team created a charter that outlined the scope of the project and what the team would deliver to WCC by the end of the project. The team agreed to …