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Full-Text Articles in Medicine and Health Sciences

Exploring The Concept Of The Digital Educator During Covid-19, Fernando Jimenez, Gracia Sanchez, Jose Palma, Luis Miralles-Pechuán, Juan A. Botia Jan 2022

Exploring The Concept Of The Digital Educator During Covid-19, Fernando Jimenez, Gracia Sanchez, Jose Palma, Luis Miralles-Pechuán, Juan A. Botia

Articles

T In many machine learning classification problems, datasets are usually of high dimensionality and therefore require efficient and effective methods for identifying the relative importance of their attributes, eliminating the redundant and irrelevant ones. Due to the huge size of the search space of the possible solutions, the attribute subset evaluation feature selection methods are not very suitable, so in these scenarios feature ranking methods are used. Most of the feature ranking methods described in the literature are univariate methods, which do not detect interactions between factors. In this paper, we propose two new multivariate feature ranking methods based on …


The Association Between Ambient Uvb Dose And Anca‑Associated Vasculitis Relapse And Onset, Jennifer Scott, Enock Havyarimana, Albert Navarro-Gallinad, Arthur White, Jason Wyse, Jos Van Geffen, Michiel Van Weele, Antonia Buettner, Tamara Wanigasekera, Cathal Walsh, Louis Aslett, John Kelleher, Julie Power, James Ng, Declan O’Sullivan, Lucy Hederman, Neil Basu, Mark A. Little, Lina Zgaga Jan 2022

The Association Between Ambient Uvb Dose And Anca‑Associated Vasculitis Relapse And Onset, Jennifer Scott, Enock Havyarimana, Albert Navarro-Gallinad, Arthur White, Jason Wyse, Jos Van Geffen, Michiel Van Weele, Antonia Buettner, Tamara Wanigasekera, Cathal Walsh, Louis Aslett, John Kelleher, Julie Power, James Ng, Declan O’Sullivan, Lucy Hederman, Neil Basu, Mark A. Little, Lina Zgaga

Articles

The aetiology of ANCA-associated vasculitis (AAV) and triggers of relapse are poorly understood. Vitamin D (vitD) is an important immunomodulator, potentially responsible for the observed latitudinal differences between granulomatous and non-granulomatous AAV phenotypes. A narrow ultraviolet B spectrum induces vitD synthesis (vitD-UVB) via the skin. We hypothesised that prolonged periods of low ambient UVB (and by extension vitD deficiency) are associated with the granulomatous form of the disease and an increased risk of AAV relapse.