Medicine and Health Sciences Commons^™

Promoting Reading Achievement In Children With Developmental Language Disorders: What Can We Learn From Research On Specific Language Impairment And Dyslexia?, Suzanne M. Adlof

Faculty Publications

Purpose Specific language impairment (SLI; see also developmental language disorder) and dyslexia are separate, yet frequently co-occurring disorders that confer risks to reading comprehension and academic achievement. Until recently, most studies of one disorder had little consideration of the other, and each disorder was addressed by different practitioners. However, understanding how the two disorders relate to each other is important for advancing theories about each disorder and improving reading comprehension and academic achievement. The purpose of this clinical focus article is to integrate research on SLI and dyslexia as well as advocate for the consideration of comorbidities in future research …

Narrative Language Among Mothers With The Fmr1 Premutation And Mothers Of Children With Autism Spectrum Disorder, Sara Mousavi

Theses and Dissertations

Difficulties with pragmatic language are known language traits among women with the FMR1 premutation and within the broad autism phenotype (BAP). Our study investigated the narrative cohesion and story grammar organization of spontaneously generated stories produced by mothers with the FMR1 premutation, mothers of children with ASD, and mothers of typically developing children. No group differences were observed in story grammar, overall quality, or frequency of use of temporal devices. But both the mothers of children with ASD and mothers with the FMR1 premutation committed reference errors at a significantly higher frequency than mothers in the control group. This study …

Complex Syntax Acquisition In Children With Hearing Loss, Marissa Castaldo

Theses and Dissertations

Purpose: The purpose of this language sample analysis was to describe complex syntax development in children with hearing loss over the preschool years. The current study addresses the following relevant research questions: Do children with hearing loss have increased performance over preschool years on broad measures of complex syntax? and What are the developmental trajectories on complex syntax in children with hearing loss?

Methods: 9 children with hearing loss participated in a 12-minute language sample following the Hadley Protocol (1998). Each child was tested at age 4 and then again in 6-month intervals until they turned 6. These children with …

Antisaccade Performance As A Measure Of Executive Dysfunction In Women With The Fmr1 Premutation, Lyndsay Schmitt

Theses and Dissertations

Women with the FMR1 premutation appear to be at increased risk for executive dysfunction. Findings in this regard have been mixed, leading to controversy surrounding the executive phenotype. Inhibitory deficits have been a more consistently documented component of this cognitive profile (Klusek et al., 2020; Shelton et al., 2014). This study aimed to clarify the executive phenotype through use of the antisaccade task, a well referenced eye-tracking paradigm that targets oculomotor inhibition and motor control and imposes time constraints that may increase sensitivity to executive deficits in women with the FMR1 premutation. The effects of aging were examined in both …

The Relation Between Linguistic Awareness Skills And Spelling In Adults: A Comparison Among Scoring Procedures, Victoria S. Henbest, Lisa A. Fitton Ph.D., Krystal L. Werfel, Kenn Apel

Faculty Publications

Purpose: Spelling is a skill that relies on an individual’s linguistic awareness, the ability to overtly manipulate language. The ability to accurately spell is important for academic and career success into adulthood. The spelling skills of adults have received some attention in the literature, but there is limited information regarding which approach for analyzing adults’ spelling is optimal for guiding instruction or intervention for those who struggle. Thus, we aimed to examine the concurrent validity of four different scoring methods for measuring adults’ spellings (a dichotomous scoring method and three continuous methods) and to determine whether adults’ linguistic awareness skills …

Startle Response In Women With The Fmr1 Premutation And Risk For Anxiety Disorders, Azalfa Lateef

Senior Theses

Background: The FMR1 premutation, which occurs when there is an expansion of 55 -200 repeats of the CGG trinucleotide on the FMR1 gene, is associated with an increased risk for anxiety disorders. Indices of autonomic regulation may prove to be useful biomarkers for psychopathological risk, including stress and anxiety. In the general population, diminished habituation to a startle response is linked to a variety of psychological disorders, including anxiety, yet little is known about this relationship in those with the FMR1 premutation. Given the increased risk for anxiety in those with the FMR1 premutation, the present study aims to examine …

Inhibition Deficits Are Modulated By Age And Cgg Repeat Length In Carriers Of The Fmr1 Premutation Allele Who Are Mothers Of Children With Fragile X Syndrome, Jessica Klusek, Jinkuk Hong, Audra Sterling, Elizabeth Berry-Kravis, Marsha R. Mailick

Faculty Publications

Individuals who carry a premutation (PM) allele on the FMR1 gene may experience executive limitations associated with their genetic status, including inhibition deficits. However, poor understanding of individualized risk factors has limited clinical management of this group, particularly in mothers who carry the PM allele who have children with fragile X syndrome (FXS). The present study examined CGG repeat length and age as factors that may account for variable expressivity of inhibition deficits. Participants were 134 carriers of the PM allele who were mothers of children with FXS. Inhibition skills were measured using both self-report and direct behavioral assessments. Increased …