Medicine and Health Sciences Commons^™

Role Of The Default-Mode Network During Narrative Integration In Major Depressive Disorder, Darren Ri-Sheng Liang

Electronic Thesis and Dissertation Repository

How brain activity is synchronized across individuals during narrative comprehension has previously been characterized by functional magnetic resonance imaging (fMRI) in healthy and patient populations. To our knowledge, there has been limited investigation as to how it is affected by major depressive disorder (MDD). We addressed this issue with fMRI through examination of inter-subject synchronization in the default mode network (DMN), brain structures which have previously been implicated in MDD pathology. Twenty-two patients with MDD and 20 matched control participants listened to Intact versus Scrambled versions of an auditory narrative; these experimental conditions differed in the degree of temporal integration …

Assessing The Impact Of Lipopolysaccharide On Learning And Memory In Rats, Anahat Luthra

Undergraduate Student Research Internships Conference

The immune system and the central nervous system (CNS) have a bi-direction relationship, modulating one another.⁴ Proinflammatory cytokines released from CNS immune cells have an impact on cognitive processes such as learning and memory.¹ Liposaccharide (LPS), a cell wall component of Gram-negative bacteria, which is used to activate proinflammatory cytokine release has been found to impact learning and memory processes, such as in the anticipatory nausea paradigm (ANP).² Anticipatory nausea and vomiting is that which may occur before a chemotherapy treatment session begins in a patient who has had chemotherapy before. It is caused by triggers like …

Auditory Sensory Filtering And Development In Children With Autism Spectrum Disorder, Hiruthika Ravi, Ala Seif, Ryan A. Stevenson

Undergraduate Student Research Internships Conference

Sensory filtering is the process of separating and distilling relevant sensory information from irrelevant, which in turn greatly reduces the quantity of sensory information that is fully processed and leads to significant increases in efficiency. Atypical sensory filtering can result in sensory hypo- or hypersensitivity — atypical sensory filtering and hypo/hypersensitivity have been observed in people with autism. Atypical sensory filtering contributes to canonical symptoms in Autism.

Sensory filtering can be measured in a few different ways, one of which is the Acoustic Startle Response (ASR). ASR is a reflexively produced muscular reaction to sudden auditory stimuli.

Our study aims …

Seeing Thro The Musical Eye: Santo Daime, Fuke-Shū, 1960s Psychedelia, And The Antipodes Of Musical Experience, Forest Anthony-Muran

Electronic Thesis and Dissertation Repository

This thesis investigates the relationships between altered states of consciousness and the musical experience in religious tradition and practice. A common accompaniment to religious worship and ceremony, music is often used as a way of attempting to capture something of the ineffable and to help bring about a mystical experience. In this thesis, I make use of three contrasting case studies – the Brazilian syncretic religion Santo Daime, the historical branch of Zen Buddhism Fuke-shū, and the psychedelic rock of 1960s counterculture – to paint a portrait of the variety of ways that music has been used in different musical …