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Full-Text Articles in Medicine and Health Sciences
Lowering The Cost And Raising The Efficiency Of A Cure To Chagas Disease, Madeleine Peters
Lowering The Cost And Raising The Efficiency Of A Cure To Chagas Disease, Madeleine Peters
Arkansas Women in STEM Conference
Chagas disease, classified as a neglected tropical disease (NTD), is caused by the parasite Trypanosoma cruzi and is an underfunded and under researched disease. The only FDA-approved drug in the United States is benznidazole which is expensive, harmful, and only effective in the illness’ acute phase. The goal is to create a more effective, lower costing and less harmful drug by using a condensation reaction to substitute different amines to diethyl squarate (DES) to make cycloalkylsquaramides. Both DES and the amines used are relatively low in price with a simple, efficient, and high yielding synthesis. Low synthetic cost and ability …
Synthesis Of N-Benzoyl-2-Hydroxybenzamides As Agents Utilized In Treatment Of Malaria, Brittany Krug, Gregory Naumeic
Synthesis Of N-Benzoyl-2-Hydroxybenzamides As Agents Utilized In Treatment Of Malaria, Brittany Krug, Gregory Naumeic
Arkansas Women in STEM Conference
Malaria is a disease that disproportionately affects several third world countries. It is a life-threatening illness that is transmitted by mosquitoes that act as vesicles for parasites. The parasites cause a febrile illness in those that are not immune. Children under five are most susceptible to the disease which can lead to multi-organ failure and death. The disease is preventable and curable, but according to the world health organization, countries disproportionately affected cannot afford these preventative care measures or have developed resistance to treatments. Therefore it would be advantageous to develop a new treatment for malaria that focuses on cost …