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Full-Text Articles in Medicine and Health Sciences

Medicinal Plants’ Stress Factors: Effects On Metabolites And Novel Perspectives For Tolerance, Mayssaloune Ali Kanso, Mohamad Ali Hijazi, Maha Aboul Ela Prof., Abdalla El-Lakany Oct 2022

Medicinal Plants’ Stress Factors: Effects On Metabolites And Novel Perspectives For Tolerance, Mayssaloune Ali Kanso, Mohamad Ali Hijazi, Maha Aboul Ela Prof., Abdalla El-Lakany

BAU Journal - Health and Wellbeing

Medicinal plants are rich in secondary metabolites representing different chemical classes and synthesized by various biochemical pathways. However, these compounds are susceptible to potential herbal predators and to environmental influences. Several factors induce different biotic and abiotic stresses (drought, cold, salinity, heat) that lead to fluctuations in the biogenesis and accumulation of secondary metabolites by which plants react to overcome the threatening stress conditions. This contribution aims to give an overview of the various medicinal plant defense mechanisms against imminent threats and their impact on secondary metabolites profiles in the most effective medicinal plant species such as the levels of …


Interleukin-16 Rs4778889 Polymorphism And Its Interaction With Interleukin-10 Rs1800896 Polymorphism Increase The Risk For Knee Osteoarthritis In The Lebanese Population, Zeina El-Ali, Fouad Ziade, Hassan Zmerly, Nisrine Bissar Apr 2022

Interleukin-16 Rs4778889 Polymorphism And Its Interaction With Interleukin-10 Rs1800896 Polymorphism Increase The Risk For Knee Osteoarthritis In The Lebanese Population, Zeina El-Ali, Fouad Ziade, Hassan Zmerly, Nisrine Bissar

BAU Journal - Health and Wellbeing

To investigate the effect Interleukin-16 (IL-16) and Interleukin-10 (IL-10) polymorphisms, and their interaction, on knee osteoarthritis (KOA) risk in the Lebanese population. Kompetitive Allele Specific PCR (KASP) genotyping assay was performed to determine IL-16 rs4778889, rs11556218, and rs4072111 and IL-10 rs1800896 polymorphisms in 118 patients diagnosed with KOA ( ≥ 2 points on Kellgren-Lawrence (K&L) radiological classification scale) and 70 controls matched for age and gender (K&L score ≤ 1). After adjusting for age, gender, presence of metabolic disorders, smoking and drinking status, our findings suggest that rs4778889 TT genotype increases the risk for KOA compared to the combined CC …


Assessment Of The Lebanese Community Pharmacist Knowledge, Practice And Barriers Regarding The Prevention Of Osteoporosis, Noura Issa Khram, Maha Aboul Ela, Mohamad Ali Hijazi, Lama Soubra Apr 2022

Assessment Of The Lebanese Community Pharmacist Knowledge, Practice And Barriers Regarding The Prevention Of Osteoporosis, Noura Issa Khram, Maha Aboul Ela, Mohamad Ali Hijazi, Lama Soubra

BAU Journal - Health and Wellbeing

Osteoporosis is a silent skeletal disease that is often recognized when fractures occur as a result of minimal trauma. Limited studies have assessed the degree of pharmacists’ involvement in osteoporosis prevention, risk-assessment/screening and physician referrals. To assess the Lebanese community pharmacists’ knowledge, practice and barriers regarding osteoporosis prevention. Secondary aim is to assess the pharmacists’ ability to identify high-risk patients who should be referred for bone mineral density (BMD) testing. A cross-sectional study was carried out in Beirut, Lebanon between September and October 2020 using self-administered questionnaire. Pharmacists completed a multi-component questionnaire that consisted of socio-demographic characteristics, practices, knowledge and …