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Biosimilars: Exploring The History, Science And Proogress, Joseph D. Tariman Phd Sep 2018

Biosimilars: Exploring The History, Science And Proogress, Joseph D. Tariman Phd

Joseph D Tariman PhD, RN, ANP-BC, FAAN

BACKGROUND: Biosimilars provide opportunities for improving healthcare access and outcomes and reducing overall healthcare costs for patients with cancer.
OBJECTIVES: The purpose of this article is to explore the history of biosimilars, regulatory pathways, and barriers to biosimilar approval. This article also aims to describe the patient and clinician barriers to biosimilars use and the progress that has been achieved since the first biosimilar approval in Europe in 2006 and in the United States in 2015.
METHODS: A literature search was conducted to retrieve articles that are highly relevant to the history of biosimilars development and regulatory pathways in the …

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Obesity: The Bioethics We Need Now, Or What We Owe To Each Other, Lee T. Nutini Jan 2009

Obesity: The Bioethics We Need Now, Or What We Owe To Each Other, Lee T. Nutini

Lee T Nutini

This is an essay written to address the philosophical and food industrial practices underlying the current obesity epidemic in the United States. It appears in its modified lecture format, given at Yale University in 2009. As such, citations are not included. For any question about a specific citation, please contact the author directly.

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Sacred Disease Of Our Times: Failure Of The Infectious Disease Model Of Spongiform Encephalopathy, Vivian Mcalister May 2005

Sacred Disease Of Our Times: Failure Of The Infectious Disease Model Of Spongiform Encephalopathy, Vivian Mcalister

Vivian C. McAlister

BACKGROUND: Public health and agricultural policy attempts to keep bovine spongiform encephalopathy out of North America using infectious disease containment policies. Inconsistencies of the infectious disease model as it applies to the spongiform encephalopathies may result in failure of these policies.

METHODS: Review of historical, political and scientific literature to determine the appropriate disease model of spongiform encephalopathy.

PRINCIPAL FINDINGS: Spongiform encephalopathy has always occurred sporadically in man and other animals. Hippocrates may have described it in goats and cattle. Transmission of spongiform encephalopathy between individuals is too uncommon for it to be usefully considered an infection. Spongiform encephalopathy is …

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