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Full-Text Articles in Medicine and Health Sciences
Enhancement Of Immune Response For Newcastle Disease Vaccine Using A Combined Adjuvant Solution Of Astragalus Polysaccharides, Levamisole, And Selenoprotein, Yaogui Sun, Xiaojing Xie, Junping He, Junbing Jiang, Ruiyan Niu, Yuansheng Bai, Hongquan Li
Enhancement Of Immune Response For Newcastle Disease Vaccine Using A Combined Adjuvant Solution Of Astragalus Polysaccharides, Levamisole, And Selenoprotein, Yaogui Sun, Xiaojing Xie, Junping He, Junbing Jiang, Ruiyan Niu, Yuansheng Bai, Hongquan Li
Turkish Journal of Veterinary & Animal Sciences
The Newcastle disease vaccine strain I (ND I vaccine) was reconstituted using a 3-component combined adjuvant solution containing Astragalus polysaccharide (APS), levamisole (LMS), and selenoprotein (Se). A total of 200 Hy-Line brown chickens, 60 days of age, were randomly assigned into 10 groups. The first group was a negative control and was immunized using the phosphate buffered saline-reconstituted vaccine. The other 9 groups were immunized using the vaccine reconstituted with the combined adjuvant solution. The serum and blood samples were collected on days 7, 14, 21, 27, 35, and 42 after the vaccinations and were analyzed for IgG, IL-2, and …
Levamisole Enhances Global And Differential Leukocyte Numbers In Peripheral Blood Of Dogs With Ehrlichiosis, Dhagma Renata Denis Souza, Andreia Lima Tome Melo, Livia Saab Muraro, Daniel Moura Aguiar, Deijanira Albuquerque
Levamisole Enhances Global And Differential Leukocyte Numbers In Peripheral Blood Of Dogs With Ehrlichiosis, Dhagma Renata Denis Souza, Andreia Lima Tome Melo, Livia Saab Muraro, Daniel Moura Aguiar, Deijanira Albuquerque
Turkish Journal of Veterinary & Animal Sciences
Ehrlichiosis is a disease caused by Ehrlichia, a genus of obligatory intracellular bacteria that parasitize leukocytes and provoke several hematological alterations. In this work, we investigated the effect of levamisole associated with doxycycline on peripheral leukocytes in dogs PCR-positive for ehrlichial DNA. Twenty-one Ehrlichia-infected dogs were randomly distributed in 2 groups: a control group (n = 10) and a levamisole-treated group (n = 11). Blood samples were collected from each animal for hematological and DNA analysis both before initiating the experiment and 5 days later. All dogs were treated with doxycycline (10 mg/kg body weight), cimetidine (5 mg/kg of body …