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Full-Text Articles in Medicine and Health Sciences
Pathological And Immunohistochemical Studies In Rabbits Experimentally Infected With Toxoplasma Gondii, Rifki Haziroğlu, Kürşat Altintaş, Ayhan Atasever, M. Yavuz Gülbahar, Oğuz Kul, Recai̇ Tunca
Pathological And Immunohistochemical Studies In Rabbits Experimentally Infected With Toxoplasma Gondii, Rifki Haziroğlu, Kürşat Altintaş, Ayhan Atasever, M. Yavuz Gülbahar, Oğuz Kul, Recai̇ Tunca
Turkish Journal of Veterinary & Animal Sciences
Experimental toxoplasmosis was induced in rabbits using different routes. A total of 42 animals were used; 36 of them were in the experimental groups and the other six comprised the control group. In addition, five guinea pigs were used for preparing hyperimmune sera against Toxoplasma gondii. The Ankara strain was inoculated intravenously (group I, n: 12), intraperitoneally (group II, n: 12) and intradermally (group III, n: 12) into the rabbits. Group IV animals were kept as controls (n: 6). Clinical and macroscopical findings varied according to the routes of inoculation and organs affected. Microscopically, multifocal necrosis with T. gondii tachyzoites …
The Use Of Sodium Carboxymethylcellulose To Prevent Intraabdominal Adhesions In Rabbits, Yilmaz Koç, Fahretti̇n Alkan, Ayşen Uyaroğlu
The Use Of Sodium Carboxymethylcellulose To Prevent Intraabdominal Adhesions In Rabbits, Yilmaz Koç, Fahretti̇n Alkan, Ayşen Uyaroğlu
Turkish Journal of Veterinary & Animal Sciences
The purpose of the study was to evaluate the effect of a 1% sodium carboxymethylcellulose (SCMC) solution on the prevention of experimentally induced intraabdominal adhesions in rabbits. Thirty rabbits were used and divided into two equal groups. In all rabbits in both groups, ventral midline laparotomies and serosal abrasions on the caecum were performed. In the treatment group, a solution of SCMC and in the control group a NaCI solution were infused into the abdominal cavity before and after manipulations. Seven days after surgery all rabbits again underwent relaparotomy via a paramedian incision to evaluate adhesion. Adhesions were designated as …
The Investigation Of The Effects Of Pistacia Terebinthus L. Upon Experimentally Induced Hypercholesterolemia And Atherosclerosis In Rabbits, Tülay Bakirel, Süleyman Şener, Utku Bakirel, Oya Keleş, Gülbi̇n Şennazli, Aydin Gürel
The Investigation Of The Effects Of Pistacia Terebinthus L. Upon Experimentally Induced Hypercholesterolemia And Atherosclerosis In Rabbits, Tülay Bakirel, Süleyman Şener, Utku Bakirel, Oya Keleş, Gülbi̇n Şennazli, Aydin Gürel
Turkish Journal of Veterinary & Animal Sciences
The possible pharmacological and toxicological effects of Pistacia terebinthus L. in experimentally hypercholesterolemic rabbits were investigated in this study. A total of 28 rabbits were divided into four groups, and these groups were fed diets containing standard pellets (Group 1), cholesterol (2%) (Group II), P. terebinthus L. (1 g/kg body weight) and cholesterol (2%) (Group III) and P. terebinthus L. (1 g/kg body weight) (Group IV) for 14 weeks. When the data were statistically evaluated over the weeks, body weight gains, showed no marked difference among the groups although liver weight was 58% higher in the cholesterol control group (P < 0.01) and 20.3% higher in P. terebinthus L. and cholesterol group than in the control group. In the comparison of the cholesterol-fed groups, Group III exhibited a marked decrease (P < 0.01) in total cholesterol and triglyceride evels and very low density lipoprotein (VLDL) and low density lipoprotein (LDL) levels by the 14th week and a 1.3-times higher (P < 0.001) high density lipoprotein (HDL) value. In the group fed cholesterol and P. terebinthus L., clotting and bleeding times increased by 13% and 12%, respectively, compored to the cholesterol control group. On account of the histopathological findings, it was confirmed that P. terebinthus L. restrained the progression of the atherosclerotic lesions in the thoracic artery and of hydropic degeneration and fatty changes in the liver. No toxic effect could be attributed to P. terebinthus L. from an investigation of the biochemical data. The results of this study show that P. terebinthus L. has a hypolipidemic effect in hypercholesterolemic rabbits.