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The Urinary Proteomic Analysis And The Vitamin D Receptor Polymorphisms In Dogs With Calcium Oxalate Urolithiasis, Sumonwan Chamsuwan
The Urinary Proteomic Analysis And The Vitamin D Receptor Polymorphisms In Dogs With Calcium Oxalate Urolithiasis, Sumonwan Chamsuwan
Chulalongkorn University Theses and Dissertations (Chula ETD)
Calcium oxalate (CaOx) urolithiasis is one of the most common stone components which frequently occurs in both humans and dogs. Hypercalciuria is one of the predisposing factors commonly found in both people and dogs with calcium urolithiasis. The genetic factors are also involved with the pathogenesis of stone formation, and the relationship between calcium handling and vitamin D receptor (VDR) polymorphisms has been demonstrated to be related to calcium urolithiasis in human populations. Moreover, some urinary proteins may be involved in the process of stone formation. The present study aimed firstly to evaluate the relationship between VDR polymorphism in dog …