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Full-Text Articles in Medicine and Health Sciences
Review Of The P53 Tumor Suppressor Gene And Its Role In Gliomas, James Dearing Christian
Review Of The P53 Tumor Suppressor Gene And Its Role In Gliomas, James Dearing Christian
Theses and Dissertations
The following review of the p53 tumor suppressor gene will be discussed with particular attention to its role in human gliomas, as well as the various advances that have brought this molecule to the forefront of cancer research. A review of tumorigenesis focuses on the molecular mechanisms that convey neoplastic characteristics upon a normal cell. It is discussed how the coordinate advances in chromosome analysis and molecular techniques enabled the p53 gene to be categorized as a "tumor suppressor gene" and applied to various forms of cancer, including colorectal and lung carcinoma. The focus of the review will be on …
Radiosurgery For Malignant Brain Tumors, Michael Jino Yun
Radiosurgery For Malignant Brain Tumors, Michael Jino Yun
Theses and Dissertations
Radiosurgery using the Linear Accelerator or the Gamma Knife has proven to be an effective treatment modality for malignant brain tumors. In comparison to other treatments, radiosurgery can be performed on an outpatient basis and is noninvasive (Table 5). Due to the functional properties of radiosurgical devices, they are ideal for patients who are unable to undergo surgical removal of their brain tumors. The sharp dose drop—off beyond the tumor margin allows for high dosage tumor irradiation while sparing normal brain tissue. Many procedures that involve radiosurgery use it as a ”boost” therapy in conjunction with surgical resection and whole …