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Anatomy

Selected Works

2001

Articles 1 - 2 of 2

Full-Text Articles in Medicine and Health Sciences

Methods For Volume Measurement In 3d Images, Kevin J. Black Jan 2001

Methods For Volume Measurement In 3d Images, Kevin J. Black

Kevin J. Black, MD

This letter attempted to politely direct readers of a later, remarkably similar publication to my original publication. The full text as submitted is attached as a PDF file.
The poster cited in the attached letter is available here.
ADDENDUM: Approximately the same work as the article discussed in this letter was also published as: Rajapakse JC: Random-grid stereologic volumetry of MR head scans. J Magn Reson Imaging 12:833-841, 2000. I wrote a similar, unpublished letter to the editor of JMRI in 12/2000.

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Aggregated Dsred-Tagged Cx43 And Over-Expressed Cx43 Are Targeted To Lysosomes In Human Breast Cancer Cells, H. Qin, Q. Shao, Daniel Belliveau, D. Laird Dec 2000

Aggregated Dsred-Tagged Cx43 And Over-Expressed Cx43 Are Targeted To Lysosomes In Human Breast Cancer Cells, H. Qin, Q. Shao, Daniel Belliveau, D. Laird

Daniel J. Belliveau

To investigate if either wild-type or aggregated Cx43 is abnormally targeted to lysosomes in human breast tumor cells, we examined the fate of DsRed-tagged Cx43 and over-expressed Cx43 in communication-deficient HBL-100 and MDA-MB-231 cells. DsRed-tagged Cx43 was assembled into gap junctions in control normal rat kidney cells that express endogenous Cx43 but not in Cx43-negative HBL-100 cells. However, when HBL-100 cells were engineered to coexpress wild-type Cx43 a population of DsRed-tagged Cx43 was rescued and assembled into gap junctions. Co-expression of wild-type Cx26 failed to rescue the assembly of DsRed-tagged Cx43 into gap junctions. Immunolocalization studies revealed that DsRed-tagged Cx43 …

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