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Full-Text Articles in Medicine and Health Sciences

Indwelling Pleural Catheterization Maximizes Functionality And Quality Of Life In Management Of Recurrent Malignant Pleural Effusions, Avinash Ramkissoon Dec 2022

Indwelling Pleural Catheterization Maximizes Functionality And Quality Of Life In Management Of Recurrent Malignant Pleural Effusions, Avinash Ramkissoon

Clinical Research in Practice: The Journal of Team Hippocrates

A clinical decision report using:

Davies HE, Mishra EK, Kahan BC, et al. Effect of an indwelling pleural catheter vs chest tube and talc pleurodesis for relieving dyspnea in patients with malignant pleural effusion: The TIME2 randomized controlled trial. J Am Med Assoc. 2012;307(22):2383-2389. https://doi.org/10.1001/jama.2012.5535

for the management of recurrent malignant pleural effusions in a patient with metastatic renal cell carcinoma.


In-Vitro Validation Of Intratumoral Modulation Therapy For Glioblastoma, Abdulla Elsaleh Aug 2022

In-Vitro Validation Of Intratumoral Modulation Therapy For Glioblastoma, Abdulla Elsaleh

Undergraduate Student Research Internships Conference

Intratumoral modulation therapy (IMT) is a novel electrotherapy used to treat brain cancer tumours using electric fields applied directly to the tumours through implanted electrodes. Previous research has validated IMT's effectiveness and provided computer-simulated optimizations for IMT electric fields. This work validates these computer optimizations in-vitro, using a PCB construct to deliver electric fields, and bioluminescence imaging to assess cell viability.

We found electric field strength to correlate with cell viability, and found that rotating (phase-shifted) electric fields did not produce significant improvements in IMT efficacy. Future work will investigate different IMT frequencies and other parameters, while providing biological replicates …


Foundations Of Plasmas For Medical Applications, T. Von Woedtke, Mounir Laroussi, M. Gherardi May 2022

Foundations Of Plasmas For Medical Applications, T. Von Woedtke, Mounir Laroussi, M. Gherardi

Electrical & Computer Engineering Faculty Publications

Plasma medicine refers to the application of nonequilibrium plasmas at approximately body temperature, for therapeutic purposes. Nonequilibrium plasmas are weakly ionized gases which contain charged and neutral species and electric fields, and emit radiation, particularly in the visible and ultraviolet range. Medically-relevant cold atmospheric pressure plasma (CAP) sources and devices are usually dielectric barrier discharges and nonequilibrium atmospheric pressure plasma jets. Plasma diagnostic methods and modelling approaches are used to characterize the densities and fluxes of active plasma species and their interaction with surrounding matter. In addition to the direct application of plasma onto living tissue, the treatment of liquids …


A Review Of Monte Carlo Methods And Their Application In Medical Physics For Simulating Radiation Transport, Joe Shields Jan 2022

A Review Of Monte Carlo Methods And Their Application In Medical Physics For Simulating Radiation Transport, Joe Shields

Honors Theses and Capstones

Monte Carlo methods are used to calculate statistical behavior through the use of random number generators and probability density functions. They have been used extensively in medical physics for research in radiotherapy, designing technology, dosimetry, and advanced clinical applications. This paper provides a background on Monte Carlo methods and a review of radiation therapy physics and dosimetry. Additionally, there is a discussion of the different ways Monte Carlo methods are used in medical physics as well as a review of current research related to Monte Carlo methods. The final portion of this paper contains my own Monte Carlo simulation using …