Medicine and Health Sciences Commons^™

Brown Adipose Tissue (Bat) Activation And Its Potential Utilization As A Treatment Option For Obesity And Diabetes, Darcie B. Schneider

Student Publications

Within the human body, there are two types of adipose tissue: white adipose tissue (WAT) and brown adipose tissue (BAT). WAT is beneficial for insulation whereas BAT has thermogenic capacity. BAT activation increases energy consumption via heat generation. Increased energy expenditure is associated with improved glucose and lipid metabolism. Therefore, BAT activation research has primarily been aimed at its potential use in the treatment of obesity, diabetes, and other metabolic disorders. In this literature review, BAT's thermogenic mechanisms, techniques of activation, potential therapeutic targets, and future research topics are explored.

Brown Fat In Humans: The Significance Of Thermogenic Active Tissue, Brett T. Swanson

Student Publications

Brown adipose tissue is a metabolically active form of fat in the body that performs a crucial function in non-shivering thermogenesis. It can be compared to the prevalent white adipose tissue which is generally understood to be energy storage in the body, with brown tissue performing an opposing role. The tissue itself contains unique gene and protein markers such as uncoupling protein 1 (UCP1) which allows for the thermogenic process inside the cell, burning lipids to do so. These gene and protein markers have proven to be crucial in the detection of brown adipose tissue, which had previously been thought …

Hyperbaric Oxygen Therapy And Wound Healing, Karen E. Lucero Ortega

Student Publications

Hyperbaric Oxygen Therapy (HBOT) has been around since the 1860s and is now a well-established form of treatment. HBOT has been proven to be a safe therapeutic option and has been successful in treating non-healing wounds, traumatic wounds, and radiation-induced wounds. There has also been success in treating other conditions such as inflammatory bowel disease, carbon monoxide poisoning, and decompression sickness with HBOT. The way HBOT works is by exposing the body to 100% pure oxygen in a closed chamber, which exceeds normal atmospheric pressure by two to three times. With HBOT, large amounts of oxygen enters the body, which …

New Developments In Hyperbaric Oxygen Therapy, Arden M. Scheetz

Student Publications

Hyperbaric Oxygen Therapy, or HBOT, is a form of treatment based on the inhalation of 100% pure oxygen while subjected to closed chamber or room at pressures greater than sea level (1 atmosphere, ATA) (Howell et al., 2018; Kocaman, 2020). HBOT is administered through either a mono-place chamber or a multi-place chamber. Mono-place chambers are pressurized with oxygen and are equipped to handle a single person at a time. Multi-place chambers, on the other hand, can accommodate up to 20 people at a time, including medical personnel and intubated patients. These chambers are pressurized with air, and pure oxygen is …

Hyperbaric Oxygen Therapy: Effect On Wound Healing And Traumatic Brain Injuries, Sara L. Seuffert

Student Publications

Hyperbaric Oxygen Therapy is a new form of treatment being used to heal and help improve symptoms of traumatic brain injuries, external wounds, and strokes. HBOT helps to completely saturate hemoglobin with oxygen, which then allows for a larger capacity of oxygen to be delivered to the damaged tissues. Tissue wounds benefit from this HBOT because of the increase in oxygen supply to the damaged area, helping to combat hypoxia, which is preventing proper wound healing. The increase in oxygen allows for an increase in myofibroblast differentiation to allow the healing process to continue. HBOT has also proven to increase …

Today's Fibromyalgia, Mckenzie K. Glennon

Student Publications

Fibromyalgia is a chronic musculoskeletal disorder which results in widespread pain, fatigue, cognitive difficulties, and emotional distress (CDC, 2017). It is also associated with abnormal pain processing. About 2% of US adults have Fibromyalgia, and the disease is more common in middle-aged women, particularly those who have other illnesses like Lupus or Rheumatoid Arthritis (CDC, 2017). The exact cause of the disease is unknown, but it is likely a combination of genetics, infections and physical and emotional trauma. Since the exact cause of Fibromyalgia is unknown, treatment options vary. Medication, stress management techniques and an exercise plan are all examples …

Reflexology, Kristen A. Quindlen

Student Publications

Reflexology is the practice of applying pressure to particular points on the ears, hands and feet to impact the health of specific parts of the body. It is a form of complementary therapy that is used for diseases and conditions that have long lasting symptoms and need pain management. In reflexology, each pressure point acts as a sensor on the feet and hands and is linked with organs, glands and muscles in specific parts of the body. It involves the idea that a force or energy is flowing along paths, called meridians, in the body to all organs and any …

Amyotrophic Lateral Sclerosis, Anastasia M. Georgetson

Student Publications

The word amyotrophic is derived from Greek, and means “without nourishment to muscles”, lateral means to the sides and sclerosis means hardened (“What is ALS?,” n.d.). First described by Jean-Martin Charcot in the 1800s, Amyotrophic Lateral Sclerosis (ALS) is a progressive degenerative motor neuron disease. Motor neurons are very important cells, and extremely unique since they can be very long with some motor neurons having a length of over a meter (“Disease Mechanisms,” n.d.).

About 5-10% of the cases of ALS are inherited, which is known as familial ALS or fALS, and it is known as autosomal dominant in these …