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Full-Text Articles in Medicine and Health Sciences
Improvements In Four-Dimensional And Dual Energy Computed Tomography, Rachael M. Martin
Improvements In Four-Dimensional And Dual Energy Computed Tomography, Rachael M. Martin
Dissertations & Theses (Open Access)
Dual energy and 4D computed tomography (CT) seek to address some of the limitations in traditional CT imaging. Dual energy CT, among other purposes, allows for the quantification and improved visualization of contrast materials, and 4D CT is often used in radiation therapy applications as it allows for the visualization and quantification of object motion. While much research has been done with these technologies, areas remain for potential improvement, both in preclinical and clinical settings, which will be explored in this dissertation. Preclinical dual energy cone-beam CT (CBCT) can benefit from wider separation between the peak energy of the two …
Design And Optimization Of Four-Dimensional Cone-Beam Computed Tomography In Image-Guided Radiation Therapy, Moiz Ahmad
Design And Optimization Of Four-Dimensional Cone-Beam Computed Tomography In Image-Guided Radiation Therapy, Moiz Ahmad
Dissertations & Theses (Open Access)
The influence of respiratory motion on patient anatomy poses a challenge to accurate radiation therapy, especially in lung cancer treatment. Modern radiation therapy planning uses models of tumor respiratory motion to account for target motion in targeting. The tumor motion model can be verified on a per-treatment session basis with four-dimensional cone-beam computed tomography (4D-CBCT), which acquires an image set of the dynamic target throughout the respiratory cycle during the therapy session. 4D-CBCT is undersampled if the scan time is too short. However, short scan time is desirable in clinical practice to reduce patient setup time. This dissertation presents the …