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Articles 1 - 12 of 12
Full-Text Articles in Medicine and Health Sciences
Evidence Of Progressive Delay Of Motor Development In Children With Sensorineural Hearing Loss And Concurrent Vestibular Dysfunction, Rose Rine, Gabrielle Cornwall, Karen Gan, Christian Locascio, Todd O'Hare, Emily Robinson, Michele Rice
Evidence Of Progressive Delay Of Motor Development In Children With Sensorineural Hearing Loss And Concurrent Vestibular Dysfunction, Rose Rine, Gabrielle Cornwall, Karen Gan, Christian Locascio, Todd O'Hare, Emily Robinson, Michele Rice
Rose Marie Rine P.T., Ph.D.
Gross motor development, and the effect of age, sex and vestibular function on it, was examined in 39 24- to 83-mo.-old children with sensorineural hearing impairment. Repeated testing was completed on 18 children. Delayed gross motor development was evident regardless of age, but only children less than 5 years of age had developmental balance deficits on initial testing. Both gross motor and balance development scores were lower on repeated testing. Furthermore, vestibular function scores facilitated identification of those children with a deficit in balance development as well as those with a progressive delay in motor or balance development. Implications for …
Antipsychotic Use In Nursing Homes Varies By Psychiatric Consultant, Jennifer Tjia, Terry Field, Celeste Lemay, Kathleen Mazor, Michelle Pandolfi, Ann Spenard, Shih-Yieh Ho, Abir Kanaan, Jennifer Donovan, Jerry Gurwitz, Becky Briesacher
Antipsychotic Use In Nursing Homes Varies By Psychiatric Consultant, Jennifer Tjia, Terry Field, Celeste Lemay, Kathleen Mazor, Michelle Pandolfi, Ann Spenard, Shih-Yieh Ho, Abir Kanaan, Jennifer Donovan, Jerry Gurwitz, Becky Briesacher
Jennifer Tjia
BACKGROUND: The relationship between psychiatric consultation and antipsychotic prescribing in nursing homes (NH) is unknown. OBJECTIVE: To identify the association between psychiatric consultant groups and NH-level antipsychotic prescribing after adjustment for resident case-mix and facility characteristics. RESEARCH DESIGN AND SUBJECTS: Nested cross-sectional study of 60 NHs in a cluster randomized trial. We linked facility leadership surveys to October 2009-September 2010 Minimum Data Set, Nursing Home Compare, the US Census, and pharmacy dispensing data. MEASURES: The main exposure is the psychiatric consultant group and the main outcome is NH-level prevalence of atypical antipsychotic use. We calculated annual means and interquartile ranges …
Two Brief Interventions For Acute Pain, Stephen Bruehl, Charles Carlson, James Mccubbin
Two Brief Interventions For Acute Pain, Stephen Bruehl, Charles Carlson, James Mccubbin
James A. McCubbin
This study evaluated two brief (3–5 min) interventions for controlling responses to acute pain. Eighty male subjects were randomly assigned to 1 of 2 intervention groups (Positive Emotion Induction (PEI) or Brief Relaxation (BR)) or to 1 of 2 control groups (No-instruction or Social Demand). The PEI focused on re-creating a pleasant memory, while the BR procedure involved decreasing respiration rate and positioning the body in a relaxed posture. All subjects underwent a 60-sec finger pressure pain trial. Analyses indicated that the PEI subjects reported lower ratings of pain, fear, and anxiety, and experienced greater finger temperature recovery than controls. …
Psychological Coping With Acute Pain: An Examination Of The Role Of Endogenous Opioid Mechanisms, Stephen Bruehl, Charles Carlson, John Wilson, Jane Norton, George Colclough, Marianne Brady, Jeffrey Sherman, James Mccubbin
Psychological Coping With Acute Pain: An Examination Of The Role Of Endogenous Opioid Mechanisms, Stephen Bruehl, Charles Carlson, John Wilson, Jane Norton, George Colclough, Marianne Brady, Jeffrey Sherman, James Mccubbin
James A. McCubbin
This study examined the relationship among endogenous opioids, Monitoring and Blunting coping styles, and acute pain responses. Fifty-eight male subjects underwent a 1-min pressure pain stimulus during two laboratory sessions. Subjects experienced this pain stimulus once under endogenous opioid blockade with naltrexone and once in a placebo condition. Blunting was found to be negatively correlated with pain ratings, but this relationship was significantly more prominent under opioid blockade. Results for coping behaviors subjects used to manage the experimental pain were generally consistent with the Blunting results, indicating that cognitive coping was related more strongly to decreased pain ratings and cardiovascular …
The Relationship Between Pain Sensitivity And Blood Pressure In Normotensives, Stephen Bruehl, Charles Carlson, James Mccubbin
The Relationship Between Pain Sensitivity And Blood Pressure In Normotensives, Stephen Bruehl, Charles Carlson, James Mccubbin
James A. McCubbin
Hypertension has been found to be related to decreased sensitivity to painful stimuli. The current study explored whether this relationship extends into the normotensive range of blood pressures. Resting blood pressures were assessed in 60 male normotensives. Subjects then underwent a l min finger pressure pain stimulation trial. Pain ratings were inversely related to resting systolic blood pressure. This relationship was unrelated to emotional state or coping styles. Multiple regression analyses indicated that over one-third of the variance in pain ratings can be accounted for by resting blood pressure, coping style, and emotional state.
Comparison Of Insulin Infusion Protocols Targeting 110-140 Mg/Dl In Patients After Cardiac Surgery., Vasudev Magaji, Shriddha Nayak, Amy Donihi, Lauren Willard, Srinivasa Jampana, Parachur Nivedita, Raymond Eder, Jann Johnston, Mary Korytkowski
Comparison Of Insulin Infusion Protocols Targeting 110-140 Mg/Dl In Patients After Cardiac Surgery., Vasudev Magaji, Shriddha Nayak, Amy Donihi, Lauren Willard, Srinivasa Jampana, Parachur Nivedita, Raymond Eder, Jann Johnston, Mary Korytkowski
Vasudev G Magaji MD, MS
BACKGROUND: Continuous intravenous insulin infusion (CII) following coronary artery bypass graft (CABG) surgery reduces postoperative complications and hospitalization duration. Because of limited data evaluating outcomes of CII with revised glycemic targets (110-140 mg/dL) in cardiac surgery, this study compared efficacy and safety of two different CII protocols having revised targets. SUBJECTS AND METHODS: This is a retrospective study comparing two different protocols between August 2009 and March 2010. Protocol 1 consists of four algorithms, and Protocol 2 is a table to adjust CII. Blood glucose (BG) and CII rates were recorded for 48 h postoperatively or CII discontinuation. Efficacy was …
Human Treg Responses Allow Sustained Recombinant Adeno-Associated Virus-Mediated Transgene Expression, Christian Mueller, Jeffrey Chulay, Bruce Trapnell, Margaret Humphries, Brenna Carey, Robert Sandhaus, Noel Mcelvaney, Louis Messina, Qiushi Tang, Farshid Rouhani, Martha Campbell-Thompson, Ann Fu, Anthony Yachnis, David Knop, Guo-Jie Ye, Mark Brantly, Roberto Calcedo, Suryanarayan Somanathan, Lee Richman, Robert Vonderheide, Maigan Hulme, Todd Brusko, James Wilson, Terence Flotte
Human Treg Responses Allow Sustained Recombinant Adeno-Associated Virus-Mediated Transgene Expression, Christian Mueller, Jeffrey Chulay, Bruce Trapnell, Margaret Humphries, Brenna Carey, Robert Sandhaus, Noel Mcelvaney, Louis Messina, Qiushi Tang, Farshid Rouhani, Martha Campbell-Thompson, Ann Fu, Anthony Yachnis, David Knop, Guo-Jie Ye, Mark Brantly, Roberto Calcedo, Suryanarayan Somanathan, Lee Richman, Robert Vonderheide, Maigan Hulme, Todd Brusko, James Wilson, Terence Flotte
Christian Mueller
Recombinant adeno-associated virus (rAAV) vectors have shown promise for the treatment of several diseases; however, immune-mediated elimination of transduced cells has been suggested to limit and account for a loss of efficacy. To determine whether rAAV vector expression can persist long term, we administered rAAV vectors expressing normal, M-type alpha-1 antitrypsin (M-AAT) to AAT-deficient subjects at various doses by multiple i.m. injections. M-specific AAT expression was observed in all subjects in a dose-dependent manner and was sustained for more than 1 year in the absence of immune suppression. Muscle biopsies at 1 year had sustained AAT expression and a reduction …
Emergency Department Screening And Brief Intervention Of Alcohol Use Disorders: How To Do It And Does It Work?, Aaron Love, Marna Greenberg, Matthew Brice, Michael Weinstock
Emergency Department Screening And Brief Intervention Of Alcohol Use Disorders: How To Do It And Does It Work?, Aaron Love, Marna Greenberg, Matthew Brice, Michael Weinstock
Marna R Greenberg DO, MPH, FACEP
No abstract provided.
Differences In Emergency Physician And Nursing Tobacco And Alcohol Screening Patterns, Marna Greenberg, Aaron Love, J Li, Gina Sierzega, Charlotte Buckenmyer, Matthew Brice, Michael Weinstock
Differences In Emergency Physician And Nursing Tobacco And Alcohol Screening Patterns, Marna Greenberg, Aaron Love, J Li, Gina Sierzega, Charlotte Buckenmyer, Matthew Brice, Michael Weinstock
Marna R Greenberg DO, MPH, FACEP
No abstract provided.
Sexual Function Before And 1 Year After Laparoscopic Sacrocolpopexy, Charbel Salamon, Christa Lewis, Jennifer Priestley, Patrick Culligan
Sexual Function Before And 1 Year After Laparoscopic Sacrocolpopexy, Charbel Salamon, Christa Lewis, Jennifer Priestley, Patrick Culligan
Jennifer L. Priestley
Objective: This study aimed to compare sexual function before and 1 year after laparoscopic sacrocolpopexy using a porcine dermis or a polypropylene mesh material. Methods: This was a secondary analysis of sexual function measured before and 1 year after laparoscopic sacrocolpopexy in a group of 81 sexually active women participating in a randomized controlled trial comparing porcine dermis and polypropylene mesh. Sexual function was assessed using the short form of the Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ-12). Responses to individual questions from the physical domain of the PISQ-12 were also analyzed. Additional information included the type of mesh material …
Predictive Validity Of A Training Protocol Using A Robotic Surgery Simulator, Patrick Culligan, Emil Gurshumov, Christa Lewis, Jennifer Priestley, Jodie Komar, Charbel Salamon
Predictive Validity Of A Training Protocol Using A Robotic Surgery Simulator, Patrick Culligan, Emil Gurshumov, Christa Lewis, Jennifer Priestley, Jodie Komar, Charbel Salamon
Jennifer L. Priestley
Background: Robotic surgery simulation may provide a way for surgeons to acquire specific robotic surgical skills without practicing on live patients. Methods: Five robotic surgery experts performed 10 simulator skills to the best of their ability, and thus, established expert benchmarks for all parameters of these skills. A group of credentialed gynecologic surgeons naive to robotics practiced the simulator skills until they were able to perform each one as well as our experts. Within a week of doing so, they completed robotic pig laboratory training, after which they performed supracervical hysterectomies as their first-ever live human robotic surgery. Time, blood …
Brain Metastasis After Prophylactic Cranial Irradiation In Patients With Small Cell Lung Cancer, Patricia Tai, Avi Assouline, Kurian Joseph, Joseph S-K Au, Edward Yu
Brain Metastasis After Prophylactic Cranial Irradiation In Patients With Small Cell Lung Cancer, Patricia Tai, Avi Assouline, Kurian Joseph, Joseph S-K Au, Edward Yu
Edward Yu
No abstract provided.