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Understanding The Role Of Homoeopathic Preparation Of Berberis Vulgaris In Mitigation Of Sodium Oxalate- Induced Hyperoxaluria: An Experimental Approach, Bhavani Tamilarasan, Porkodi Karthikeyan, Pugazhendhi Kannan, Kalaiselvi Periandavan, Raj Manchanda, Anil Khurana, Debadatta Nayak, Shanthi Palainivelu
Understanding The Role Of Homoeopathic Preparation Of Berberis Vulgaris In Mitigation Of Sodium Oxalate- Induced Hyperoxaluria: An Experimental Approach, Bhavani Tamilarasan, Porkodi Karthikeyan, Pugazhendhi Kannan, Kalaiselvi Periandavan, Raj Manchanda, Anil Khurana, Debadatta Nayak, Shanthi Palainivelu
Indian Journal of Research in Homoeopathy
Background: Hyperoxaluria and calcium oxalate crystal deposition in the kidneys lead to overproduction of reactive oxygen species, resulting in the development of oxidative stress and renal injury. At the cellular levels, mitochondria and NADPH oxidase involved in reactive oxygen species production play a crucial role in the pathogenesis of hyperoxaluria-induced renal injury. Objective: The objective was to investigate the therapeutical effect of homoeopathic drug Berberis vulgaris, a potent antioxidant, upon regulation of NADPH oxidase against acute high-grade sodium oxalate-induced hyperoxaluria in rats. Materials and Methods: Hyperoxaluria was induced in male Wistar rats by administering a single dose of sodium oxalate …