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Full-Text Articles in Medicine and Health Sciences

An Initial Analysis Of A Long-Term Ketogenic Diet’S Impact On Motor Behavior, Brain Purine Systems, And Nigral Dopamine Neurons In A New Genetic Rodent Model Of Parkinson’S Disease, Jacob Rubin, William H. Church May 2016

An Initial Analysis Of A Long-Term Ketogenic Diet’S Impact On Motor Behavior, Brain Purine Systems, And Nigral Dopamine Neurons In A New Genetic Rodent Model Of Parkinson’S Disease, Jacob Rubin, William H. Church

Senior Theses and Projects

A growing body of research suggests that dopaminergic cell death seen in Parkinson’s disease is caused by mitochondrial dysfunction. Oxidative stress, with subsequent generation of reactive oxygen species, is the hallmark biochemical product of mitochondrial dysfunction. The ketogenic diet has been found to enhance mitochondrial energy production, protect against reactive oxygen species-generated cell death, and increase adenosine, a purine that modulates dopamine activity. The current study evaluates the effects of a long-term (5-month) ketogenic diet on behavioral, neurochemical, and neuroanatomical measures in PINK1-KO rats, a new animal model of Parkinson’s disease. Both wild-type and PINK1-KO animals fed a ketogenic diet …


Gods' Diseases: Conceptualizing The Phenomenon Of Hybridity In Sri Lanka, Anfal Yesmien Nyhan Apr 2014

Gods' Diseases: Conceptualizing The Phenomenon Of Hybridity In Sri Lanka, Anfal Yesmien Nyhan

Senior Theses and Projects

No abstract provided.


The Spirituality Of Food And Nutrition: A Critique Of The United States' Food Practices Through An Analysis Of Three Asian Religions And Philosophies, Kiley G. Hagerty Apr 2013

The Spirituality Of Food And Nutrition: A Critique Of The United States' Food Practices Through An Analysis Of Three Asian Religions And Philosophies, Kiley G. Hagerty

Senior Theses and Projects

There is no question that the United States is a country that is currently faced with serious health epidemics, such as hypertension and diabetes, associated with being overweight and obese. It has been the assumption of the government and the public that the large food corporations are to blame for the country’s poor health. However, it is too simplistic to believe that tighter regulations upon corporations would alone lead to improved health. There needs to be a change at the individual level, and of the practices of most of the country’s citizens. Through an analysis of three Asian religions (Hindu …