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Full-Text Articles in Physiology
Is Professional Breath-Hold Diving Associated With Endothelial Dysfunction?, Emilie Woehrle
Is Professional Breath-Hold Diving Associated With Endothelial Dysfunction?, Emilie Woehrle
Electronic Thesis and Dissertation Repository
Professional breath-hold diving has been linked to acute dangers; however, the long-term impacts on vascular health are unknown. The endothelium releases vasodilator substances and its functionality is an indicator of vascular health. We are testing the hypothesis that chronic exposure to severe hypoxia may alter endothelial function in breath hold divers. Divers and controls completed a flow-mediated dilation (FMD) protocol, where brachial blood flow velocity was measured following blood flow occlusion. Percent FMD was calculated as the primary measure of endothelial function. T-tests assessed the statistical significance of between-group differences. The %FMD were similar between groups (p >0.05); however, divers …
Menstrual Cycle And The Vascular Properties Of Remote Preconditioning, Shelby Rachel
Menstrual Cycle And The Vascular Properties Of Remote Preconditioning, Shelby Rachel
Electronic Theses and Dissertations
PURPOSE: A promising therapeutic intervention to counteract endothelial ischemia/reperfusion (I/R) injury is ischemic preconditioning (IPC). Limited data from ovariectomized animal models shows that estrogen deficiency abolishes the cardioprotective effects of IPC, whereas estrogen replacement restores protection. This suggests that alterations in female sex hormones, particularly estrogens, that occur naturally during the menstrual cycle is likely to influence the vascular protective properties of IPC. The aim of the present study was to identify how changes in female sex hormones that occur naturally during the menstrual cycle interfere with IPC to provide vascular endothelial protection in women. METHODS: Nine healthy premenopausal eumenorrheic …