Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- Institution
- Keyword
Articles 1 - 4 of 4
Full-Text Articles in Developmental Neuroscience
Effects Of A Circadian Mutation On Adult Neurogenesis, Michael Bahiru
Effects Of A Circadian Mutation On Adult Neurogenesis, Michael Bahiru
Masters Theses
Rotating shift work, irregular sleep patterns and jetlag disrupt circadian rhythms, induce or aggravate disease, and produce deficits in cognitive function. Internal misalignment, a state in which abnormal phase relationships prevail between and within organs, is widely proposed to account for these adverse effects of circadian disruption. This hypothesis has been difficult to test because phase shifts of the entraining environmental cycle lead to transient desynchrony. Thus, it remains possible that phase shifts, regardless of internal desynchrony, account for adverse effects of circadian disruption. I have used the duper mutant hamster, whose locomotor activity rhythms re-entrain 5-fold faster than wild …
Increased Body Weight In Adulthood Following A Peripubertal Stressor And Proposed Mechanism For Effects Of Increased Adiposity On Estrogen-Dependent Behaviors, Christina F. Gagliardi
Increased Body Weight In Adulthood Following A Peripubertal Stressor And Proposed Mechanism For Effects Of Increased Adiposity On Estrogen-Dependent Behaviors, Christina F. Gagliardi
Masters Theses
Exposure to certain stressors during a sensitive period around puberty can lead to enduring effects on an animal’s response to estradiol. In estradiol-influenced behaviors, such as sexual receptivity, hippocampal-dependent learning and memory, depression-like behavior, and anxiety-like behaviors, exposure to a peripubertal stressor such as shipping stress or an injection of lipopolysaccharide (LPS) can eliminate or even reverse the normal response to estradiol. In addition to regulating these behaviors, estradiol play a role in the regulation of body weight. While some of the previous studies touched on short-term effects on body weight, no systemic long-term study of the effects of a …
Nuclear Receptors In Ecdysone-Mediated Programmed Cell Death In Drosophila Melanogaster, Ritika Sehgal
Nuclear Receptors In Ecdysone-Mediated Programmed Cell Death In Drosophila Melanogaster, Ritika Sehgal
Masters Theses
The steroid hormone ecdysone plays vital roles during Drosophila development. Pulses of 20E during Drosophila life cycle function as temporal cues, signaling the onset of metamorphic processes, including the stage specific programmed cell death of larval tissues. Ecdysone is the critical developmental cue orchestrating the metamorphic reformation of CNS, resulting in the formation of adult-specific neural circuitry. Ecdysone signaling is transduced by a heterodimeric receptor complex formed between two nuclear receptors: EcR and Ultraspiracle (USP). There are 18 nuclear receptors known in Drosophila and EcR is the only receptor whose functions in neuronal PCD have been well recognized. Therefore, the …
A Method Of Slide-Making For Early Nervous System Study In The Chick Embryo, Roger L. Pscherer
A Method Of Slide-Making For Early Nervous System Study In The Chick Embryo, Roger L. Pscherer
Masters Theses
No abstract provided.