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Full-Text Articles in Neuroscience and Neurobiology

Nicotiana Glauca Graham (Solanaceae) Bioactivity And Toxic Effects On Mortality, Feeding Behavior And Pupation Choice Of Drosophila Melanogaster Larvae (Diptera: Drosophilidae), Abir Bouzar, Sarra Habbachi, Ibtissem Samai, Makarem Rahat, Nour El Imene Boublata, Saadane Fatma Zohra, Wafa Habbachi, Benhissen Saliha, Abdelkrim Tahraoui Dec 2022

Nicotiana Glauca Graham (Solanaceae) Bioactivity And Toxic Effects On Mortality, Feeding Behavior And Pupation Choice Of Drosophila Melanogaster Larvae (Diptera: Drosophilidae), Abir Bouzar, Sarra Habbachi, Ibtissem Samai, Makarem Rahat, Nour El Imene Boublata, Saadane Fatma Zohra, Wafa Habbachi, Benhissen Saliha, Abdelkrim Tahraoui

Journal of Bioresource Management

Nicotiana glauca is a medicinal plant used by traditional healers as antibacterial, antifungal, antiviral and anti-inflammatory medicines. The leaves of N. glauca are very rich in indolic alkaloids which give it a larvicidal power which allows us to use it as a bio-insecticide.In the present study we were perfomed in the direct (mortality) and indirect (food attractiveness and pupation) toxic effects of the aqueous extract of N. glauca on the mortality and feeding behavior of the fruit fly Drosophila melanogaster. The treatment was administered to 2nd instar larvae (L2) and the mortality rate was monitored for 15 days. Similarly we …


Examining The Diverse Effects Of Pi4ks On Synaptic Transmission And Morphology Phenotypes In Drosophila Melanogaster, Claire Richter Gorey Jan 2022

Examining The Diverse Effects Of Pi4ks On Synaptic Transmission And Morphology Phenotypes In Drosophila Melanogaster, Claire Richter Gorey

Electronic Theses and Dissertations

Phosphoinositides (PI) are lipid molecules reversibly phosphorylated by kinases at the 3’, 4’ and 5’ -OH groups of their myoinositol ring, producing seven PI species. PIs act in a dynamic and acute manner at the synapse, facilitated by multiple kinases that synthesize their respective PI species at the precise location and time. There are three phosphatidylinositol 4-kinase (PI4K) genes that encode three different PI4K enzymes (PI4KII, PI4KIIIβ (fwd) and PI4KIIIα) to synthesize PI4P (converted to PIP2), serving vital functions at the synapse. PIs participate in signaling events, protein recruitment, marking membrane identity, regulating channels and transporters, synaptic growth, …