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Full-Text Articles in Neuroscience and Neurobiology

Responding When Time Is Of The Essence: An Analysis Of Signal Timing In The Macaque Superior Colliculus During Reflexive Visually Guided Reaching, Amirhossein Asadian Aug 2024

Responding When Time Is Of The Essence: An Analysis Of Signal Timing In The Macaque Superior Colliculus During Reflexive Visually Guided Reaching, Amirhossein Asadian

Electronic Thesis and Dissertation Repository

The superior colliculus (SC) is a subcortical structure well known for contributing to saccades and reflexive orienting. SC neurons in primates are also active during arm movements, including those involving voluntary reaching. What is not known is whether SC neurons could contribute to reflexive visually guided reaches. A marker for such reaches is the express visuomotor response (EVR), which is generated on upper limb muscles in monkeys within 65 milliseconds. Here, we recorded the activity of SC neurons while two monkeys performed a task known to produce EVRs. When accounting for efferent delays, our results show that the SC neurons …


Frontoparietal Circuitry Underlying Saccade Control In The Common Marmoset, Janahan Selvanayagam Feb 2024

Frontoparietal Circuitry Underlying Saccade Control In The Common Marmoset, Janahan Selvanayagam

Electronic Thesis and Dissertation Repository

Our visual world is full of far more stimuli than can be processed simultaneously. Yet we are able to efficiently extract behaviourally relevant information from a scene, primarily by performing rapid saccadic eye movements. These processes are under the control the frontoparietal network, two critical nodes of which are: the lateral intraparietal area (LIP) and the frontal eye fields (FEF). Extensive research in the macaque has causally implicated these areas in visual attention and oculomotor control. However, the organization of the activity of single neurons in these areas across cortical layers remains poorly understood as these regions are deep within …