The Effect Of An Acute Bout Of Exercise On Postprandial Metabolic Responses In Younger And Older Adults, Hannah Frick

Masters Theses, 2010-2019

Over 370,000 Americans, primarily between the ages of 60 and 79, die annually as a result of cardiovascular disease caused by physical inactivity and a diet that is calorically dense and high in fat. Current findings in young and middle-aged adults suggest that acute exercise with energy expenditure in excess of 500 kcals, may attenuate the deleterious health effects caused by consuming the typical American meal. Purpose:The purpose of this study was to examine the effects of acute exercise and aging on postprandial lipemia (PPL) and postprandial glycemia (PPG). We hypothesized that aerobic exercise performed prior to the consumption …

Effects Of A 12-Week Vigorous Interval Training Intervention On Pro-Inflammatory Markers In Post-Operative Bariatric And Obese Participants, Brittany Rood

Masters Theses, 2010-2019

Increase prevalence of cardiovascular and other chronic diseases linked to inflammation has led to research on pro-inflammatory cytokines, like tumor necrosis factor - alpha (TNF-α) and lipoprotein-associated phospholipase A₂ (Lp-PLA₂), in attempt to define the relationship between chronic disease, inflammation, and obesity. PURPOSE: Examine the effect of twelve weeks of vigorous intensity interval training on pro-inflammatory markers in post-operative bariatric and obese participants. METHODS: 9 post-operative bariatric individuals [1 man, 8 women; Body mass index (BMI) = 34.23 ± 2.54 kg/m²], 12 obese individuals [5 men, 7 women; BMI=35.77 ± 1.67 kg/m^{2 …}

Influence Of Post-Exercise Nutrient Intake On Recovery And Subsequent Exercise Performance In Youth Cyclists, Andrew Law

Masters Theses, 2010-2019

Purpose: The purpose of this study was to determine if chocolate milk (CM) consumption after high-intensity cycling exercise affects post-exercise recovery and subsequent exercise performance in youth cyclists, compared to a carbohydrate-only (CHO) and a placebo (PL) beverage. Methods: Eight youth cyclists (15-18 y, VO_2peak = 61.8 ± 7.7 mL·kg^-1·min^-1) performed an exercise/recovery protocol consisting of 2 bouts of exercise, on 3 separate occasions, in a randomly counterbalanced crossover design. The first exercise bout (EX1) consisted of 30 min of constant-load cycling (40-60% W_max), and 60 min of high-intensity intervals (alternating 2 min …

Expiratory Flow Limitation In Elite Youth Cyclists, Katherine R. Smith

Masters Theses, 2010-2019

Expiratory flow limitation (EFL) has been reported in pre-pubescent adolescents and elite, adult endurance athletes; however, the occurrence of EFL in elite adolescent endurance athletes has not been determined. Purpose: To determine incidence and severity of EFL in elite youth male cyclists of adolescent age. We hypothesized that elite, endurance trained youth will experience a higher prevalence and severity of EFL and dyspnea compared to an untrained control group. Pulmonary function will be similar pre- to post-exercise with bronchodilation occurring in both groups. Methods: 12 elite endurance- trained (ET) youth male cyclists (16.3 ± 1.0 years; 176.5 ± …

Physiological And Anthropometric Profiles Of Elite Teen-Age Cyclists, David Lenzi

Masters Theses, 2010-2019

Lenzi D. N., N. D. Luden, C. J. Womack, and M. J. Saunders. Physiological and anthropometric profiles of elite teen-age cyclists. Purpose: Previous research has demonstrated that maximal oxygen consumption (VO2max), lactate threshold (LT), aerobic/anaerobic power output, and several anthropometric characteristics are related to elite cycling performance in adults. These values also improve during maturation in children. However, there is little research examining how these values differ between elite teen-age cyclists and their adult counterparts. Previous literature has also reported low bone mineral density (BMD) in adult cyclists when compared to recreationally active controls. This study sought to characterize the …

Circulating Microrna Following High Intensity Interval Cycling With And Without Post-Exercise Nutrient Consumption, Jeremy Via

Masters Theses, 2010-2019

Introduction: MicroRNA (miRNA) are small, non-coding RNA that act post-transcriptionally to regulate gene expression. miRNA levels are modulated by acute aerobic exercise, yet little is known about how miRNA levels may change in response to high-intensity interval exercise. Further, almost nothing is known about the impact of post-exercise nutrition (carbohydrate and/or protein) on miRNA levels. Thus, the purpose of this study is to examine the effects of high-intensity interval cycling and different post-exercise nutrients on ci-miRNA levels. Methods: Nine recreationally active males (age 21.9 ± 2.0yrs; VO_2max 49.6 ± 4.0mL/kg/min) competed three trials, each including identical exercise protocols. Protocol …

Impact Of Pre-Exercise Feedings With A Low Or High Glycemic Index On The Ergogenic Effects Of Carbohydrate Mouth-Rinsing During Cycling, Nikolai J. Hladick

Masters Theses, 2010-2019

Purpose: Carbohydrate (CHO) ingestion during exercise enhances performance in short endurance events (~ 1 hr) due to neural influences, as demonstrated by the efficacy of CHO mouth-rinsing during cycling. However, the magnitude of these neural effects may be blunted following pre-exercise CHO feedings. This study examined whether the glycemic index (GI) of a pre-exercise meal affected time-trial (TT) performance in cyclists using a CHO mouth-rinse during exercise. Methods: Eight cyclists (age: 24 ± 6 yr; VO_2max: 61 ± 8 ml×kg^-1×min^-1) completed 4 exercise trials, consisting of 15 min of constant-load cycling followed by a …

The Impact Of Freedson Bout Vs. Non-Freedson Bout Physical Activity On Metabolic Syndrome Risk In College Students, Valerie Olijar

Masters Theses, 2010-2019

Purpose The aim of this study is to examine moderate to vigorous physical activity in Freedson bouts compared to non-Freedson bouts and their association with Metabolic Syndrome risk factors in college students.

Methods 72 subjects aged 18-26 were recruited from James Madison University. Subjects height, weight, waist circumference, blood pressure, and body composition were assessed on visit 1. Blood pressure, fasted blood glucose, and lipid profile were assessed on visit 2. Subjects wore an Actigraph GT3X+ accelerometer, which measured physical activity and sleep for 7 days and nights. Univariate Pearson correlation analyses were performed to determine the relationship physical activity …

The Effect Of Menstrual Phase And Oral Contraceptive Steroids On Caffeine During Cycling Performance, Annette M. Lemanski

Masters Theses, 2010-2019

PURPOSE: There is evidence that female sex hormones impact caffeine metabolism, with decreased CYP1A2 activity and diminished caffeine clearance in women with higher estrogen levels. Therefore, the objectives of this project were to determine the effects of oral contraceptives and menstrual cycle on the benefits of caffeine supplementation for cycling performance. METHODS: Sixteen recreationally trained female cyclists, oral contraceptive steroid (OCS) users (n=8, age = 21.4 ± 1.4 years, height = 168.4 ± 3.6 cm, weight = 63.6 ± 7.2kg, VO_2max = 48.0 ± 4.0 ml/kg/min), and non-users (n=8, age = 20.9 ± 2.1 years, height = 161.0 ± …

A 16-Week Run Sprint Interval Training Does Not Have An Effect On Cardiovascular Risk Measured By Framingham Risk Score On Prediabetic Women, Joan A. Mandelson

Masters Theses, 2010-2019

The Framingham risk score (FRS) was developed to determine the likelihood of developing cardiovascular disease (CVD) in the next 10 years using an individual’s age, gender, total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), smoking habits, and systolic blood pressure (SBP). Run-sprint interval training (R-SIT) has shown improvements in various health and blood markers while reducing total exercise time. To date there has not been a study that examines the effects of R-SIT and moderate intensity training (MIT) on framingham risk. The purpose of this study was to determine if a reduction of the 10-year risk of CVD (determined by …

A Low-Carbohydrate Ketogenic Diet Combined With Six Weeks Of Crossfit Training Improves Body Composition And Performance, Rachel M. Gregory

Masters Theses, 2010-2019

A low-carbohydrate ketogenic diet (LCKD) is a popular approach to weight and fat loss. CrossFit is a high-intensity power training (HIPT) type exercise for all levels of age and fitness that has gained recognition as one of the fasting growing sports in America. No previous research has been found which examines body composition changes or performance in individuals consuming a LCKD and participating in CrossFit training. PURPOSE: The purpose of this research was to examine the effects of a 6-week LCKD and CrossFit program on body composition and performance. METHODS: Twenty-seven non-elite CrossFit subjects (mean ± SD age = …

A Single Night Of Sleep Restriction Impairs Recovery From Heavy Exercise, John D. Chase

Masters Theses, 2010-2019

We examined the effects of one night of sleep restriction (Sleep-; 2.5 hrs) on subsequent 3-km cycling performance and skeletal muscle recovery from heavy exercise compared to a full night of rest (Sleep+; 7 hrs). Seven recreational cyclists (n=6 male, n=1 female; age = 24.4 ± 7 yrs; height = 170 ± 10 cm; weight = 68 ± 13 kg VO_2max = 61.5 ± 4.4 ml/kg/min) completed four simulated 3-km time trials (TT) and six peak isokinetic torque trials at different speeds (30 and 120°/sec) under both conditions. The first exercise trial (EX1) consisted …

The Effect Of Sleep Restriction On Coagulation And Fibrinolysis After Heavy Exercise, Paul A. Roberson

Masters Theses, 2010-2019

Introduction: Research has shown exercise elicits a hemostatic response affecting coagulation and fibrinolysis. Furthermore, prior research has determined circadian fluctuations exist where clotting potential increases in the morning as a result of increased PAI-1 and decreased tPA which is further exacerbated by exercise. These circadian fluctuations and exercise responses have the potential to be accentuated by poor sleep. The purpose of this study is to determine the effects of sleep restriction on tPA activity, PAI-1 activity, and Factor VIII antigen activity (FVIII) while resting and after exercise.

Methods: 7 Subjects underwent two similar exercises sessions (EX). EX1 occurred in the …

The Influence Of Time-Of-Day Consumption And Training Status On The Ergogenic Properties Of Caffeine, James C. Boyett

Masters Theses, 2010-2019

Purpose: The objectives were to determine the effects of time-of-day consumption and training status on the benefits of caffeine supplementation for cycling performance and peak muscle strength. METHODS: Twenty untrained and trained subjects completed four trials consisting of isokinetic peak torque testing and 3-km time trials (TT). Subjects ingested either 6 mg/kg of caffeine or a placebo one hour prior to each trial. Treatments were: morning + placebo, morning + caffeine, evening + placebo, evening + caffeine. Magnitude based inferences were used to evaluate treatment differences. RESULTS: Caffeine (‘very likely’ and ‘likely’) improved 3-km TT performance in the morning and …

The Effect Of Run Sprint Interval Training On Diabetic Metabolic Markers In Prediabetic Adults, Kathryn L. Hilovsky

Masters Theses, 2010-2019

Abstract

Purpose: The primary purpose of this study was to compare the effects of an 8-week run-sprint interval training (R-SIT) and continuous moderate-intensity training (MIT) on fasting blood glucose, HbA1c, insulin sensitivity, and β-cell function in sedentary, prediabetic adults. Secondary outcomes of the study included anthropometric, body composition variables, and aerobic capacity.

Methods: Sedentary, physician diagnosed prediabetic individuals were randomized into R-SIT (n=7, BMI 36.76 ± 9.79) or MIT (n=8, BMI 40.59 ± 12.49) interventions. Subjects participated in supervised exercise three times a week and attended a Diabetes Prevention Program course, once weekly. R-SIT participants performed 4-6 x 30-second …

Satellite Cell Behavior In Cyclists Following Intensified Training With And Without Protein Supplementation, Alec I. Mckenzie

Masters Theses, 2010-2019

PURPOSE: The objectives were to determine the satellite cell (SC) response among endurance-trained cyclists (n=8; VO_2max: 63.1 ± 8.4 mL/Kg/min)to a period of intensified training (ICT) (10 days) and 10 days of recovery (RVT), with and without protein supplementation. METHODS: Muscle biopsies were obtained from the vastus lateralis prior to- and immediately following ICT and RVT. Fluorescent microscopy was used to analyze SCs and myosin heavy chain I and IIa (MHC I and IIa). Data were analyzed using magnitude-based inferences. RESULTS: MHC I SCs were exceptionally abundant at baseline (38 ± 20 SCs/100 fibers). MHC I SC count …

The Effect Of Run Sprint Interval Training On Prediabetic Adults: Health Related Quality Of Life, Perceived Enjoyment, And Exercise Adherence, Nicole M. Gilbertson

Masters Theses, 2010-2019

Abstract

Purpose: The purpose of this study is to determine if Health Related Quality of Life (HRQOL) and perceived exercise enjoyment are greater in a run sprint interval training (RSIT) group compared to a moderate intensity training (MIT) group in sedentary, prediabetic adults after an 8-week intervention.

Methods: Over 8-weeks, subjects in the RSIT group progressed from 4 to 6 30-second sprints per session, and the MIT group progressed from 30 to 60 minutes of continuous moderate intensity exercise. Participants in both groups completed 8-weeks of the Centers for Disease Control and Prevention (CDC) Diabetes Prevention Program educational classes. HRQOL …

The Association Between Sleep Quality, Physical Inactivity, And Risk Of Developing Metabolic Syndrome, Matthew Scott

Masters Theses, 2010-2019

Abstract

Purpose The aim of this study is to assess the independent effects of sedentary time, sleep quality, and physical activity on risk factors for Metabolic Syndrome (MetS) in college students.

Methods 40 college aged students were recruited from James Madison University. Height, weight, blood pressure, waist circumference, and body composition were assessed on visit 1. Blood pressure, blood glucose, and lipid profile were assessed on visit 2. Subjects were required to wear an Actigraph GT3x accelerometer, which measured physical activity, sedentary time, and sleep quality for 7 days and nights. Univariate Pearson correlation analyses were performed to determine the …

The Effects Of Sr2w-1 Supplementation On Cycling Performance And Muscle Fatigue, Tara Ali Ata

Masters Theses, 2010-2019

The purpose of this investigation was to examine the potential effects of SR2W-1 supplementation on cycling performance, central fatigue, and a variety of physiological parameters, including blood lactate, blood pH, heart rate (HR), rating of perceived exertion (RPE), oxygen consumption (VO2), expired ventilation (VE), and respiratory exchange ratio (RER). Methods: Five recreational cyclists (38 ± 8 yr, 168.4 ± 4.3 cm, 68.8 ± 5.6 kg, and 54.4 ± 2.6 mL/kg/min) performed 20-min of steady-state cycling (~85% VO2max) followed by three 1-min high intensity intervals at VO2max with 30-sec active recovery periods at 100 W, 15-min passive recovery period, and a …