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Full-Text Articles in Life Sciences

Transcriptome Analysis And Expression Of Selected Cationic Amino Acid Transporters In The Liver Of Broiler Chicken Fed Diets With Varying Concentrations Of Lysine, Collins N. Khwatenge, Boniface M. Kimathi, Samuel N. Nahashon Aug 2020

Transcriptome Analysis And Expression Of Selected Cationic Amino Acid Transporters In The Liver Of Broiler Chicken Fed Diets With Varying Concentrations Of Lysine, Collins N. Khwatenge, Boniface M. Kimathi, Samuel N. Nahashon

Agricultural and Environmental Sciences Faculty Research

Amino acids are known to play a key role in gene expression regulation. Amino acid signaling is mediated via two pathways: the mammalian target of rapamycin complex 1 (mTORC1) and the amino acid responsive (AAR) pathways. Cationic amino acid transporters (CATs) are crucial in these pathways due to their sensing, signaling and transport functions. The availability of certain amino acids plays a key role in the intake of other amino acids, hence affecting growth in young birds. However, the specific mechanism for regulating lysine transport for growth is not clear. In this study, we analyze the transcriptome profiles and mRNA ...


Improving Performance Of Finishing Pigs With Added Valine, Isoleucine, And Tryptophan: Validating A Meta-Analysis Model, H. R. Kerkaert, H. S. Cemin, J. C. Woodworth, J. M. Derouchey, S. S. Dritz, M. D. Tokach, R. D. Goodband, K. D. Haydon, C. Hastad, Z. Post Jan 2020

Improving Performance Of Finishing Pigs With Added Valine, Isoleucine, And Tryptophan: Validating A Meta-Analysis Model, H. R. Kerkaert, H. S. Cemin, J. C. Woodworth, J. M. Derouchey, S. S. Dritz, M. D. Tokach, R. D. Goodband, K. D. Haydon, C. Hastad, Z. Post

Kansas Agricultural Experiment Station Research Reports

Based on a recent meta-analysis, we hypothesized that increased dietary Val, Ile, or Trp could correct possible amino acid interactions caused by high dietary Leu in diets containing high levels of corn protein, namely dried distillers grains with solubles (DDGS). A total of 1,200 pigs (PIC TR4 × (Fast LW × PIC L02); initially 74.0 ± 1.38 lb) were used in a 103-d study. The 6 dietary treatments were corn-soybean meal- DDGS-based diets as follows: 1) low level of Lys-HCl (HSBM), 2) high Lys-HCl and moderate Ile, Val, Trp (NC; AA above NRC4 estimates), 3) moderate Lys-HCl and high Ile ...


Evaluation Of Nutritional Strategies To Reduce Growth Rate Of Pigs Beyond 200 Lb Body Weight, Z. X. Rao, J. T. Gebhardt, M. D. Tokach, J. C. Woodworth, J. M. Derouchey, R. D. Goodband Jan 2020

Evaluation Of Nutritional Strategies To Reduce Growth Rate Of Pigs Beyond 200 Lb Body Weight, Z. X. Rao, J. T. Gebhardt, M. D. Tokach, J. C. Woodworth, J. M. Derouchey, R. D. Goodband

Kansas Agricultural Experiment Station Research Reports

A total of 356 finishing pigs (DNA; 241 × 600; initially 196.3 ± 2.43 lb) were used in a 44-d growth trial to evaluate nutritional strategies to reduce growth rate of pigs beyond 200 lb body weight. A total of 3 diets were manufactured (control, Lys-deficient, and corn) and arranged into 4 nutritional strategies. In stage 1 (d 0 to 28), pens received one of two dietary treatments (control or Lys-deficient). Then on d 28, pens of pigs previously fed the control diet were separated into 2 groups, one fed the control diet and the other the corn diet. Pens ...


Evaluation Of Compensatory Growth Of 200 Lb Finishing Pigs Previously Fed A Low Lysine Diet, Z. X. Rao, J. T. Gebhardt, M. D. Tokach, J. C. Woodworth, J. M. Derouchey, Robert D. Goodband Jan 2020

Evaluation Of Compensatory Growth Of 200 Lb Finishing Pigs Previously Fed A Low Lysine Diet, Z. X. Rao, J. T. Gebhardt, M. D. Tokach, J. C. Woodworth, J. M. Derouchey, Robert D. Goodband

Kansas Agricultural Experiment Station Research Reports

A total of 346 pigs (241 × 600, DNA, Columbus, NE; initially 195.3 lb) were used in a 44-d trial to evaluate the compensatory growth of 200 lb finishing pigs previously fed a low lysine diet. Two diets were manufactured (control and corn diet) and arranged into 4 nutritional strategies. One group of pigs (control) was fed the control diet from d 0 to 44. The other three groups of pigs were fed the corn diet for 2, 3, or 4 weeks and then switched to the control diet until d 44. The control diet contained 13.0% crude protein ...