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Articles 1 - 7 of 7
Full-Text Articles in Life Sciences
Data From: Silica Induction Of Diverse Inflammatory Proteome In Lungs Of Lupus-Prone Mice Quelled By Dietary Docosahexaenoic Acid Supplementation, James Pestka, Lichchavi D. Rajasinghe, Abby D. Benninghoff
Data From: Silica Induction Of Diverse Inflammatory Proteome In Lungs Of Lupus-Prone Mice Quelled By Dietary Docosahexaenoic Acid Supplementation, James Pestka, Lichchavi D. Rajasinghe, Abby D. Benninghoff
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Repeated short-term intranasal instillation of lupus-prone mice with to crystalline silica (cSiO2) induces inflammatory gene expression and ectopic lymphoid neogenesis in the lung, leading to early onset of systemic autoimmunity and rapid progression to glomerulonephritis. These responses are suppressed by dietary supplementation with the ω-3 polyunsaturated fatty acid docosahexaenoic acid (DHA). Here, we tested the hypothesis that dietary DHA supplementation suppresses cSiO2-induced inflammatory proteins in bronchoalveolar alveolar lavage fluid (BALF) and plasma of lupus-prone mice. Archived tissue fluid samples were used from a prior investigation in which 6 wk-old lupus-prone female NZBWF1 mice were fed isocaloric diets containing 0 or …
Energy Expenditure Across Immune Challenge Severities In A Lizard: Consequences For Innate Immunity, Locomotor Performance And Oxidative Status, Susannah S. French, Spencer Hudson
Energy Expenditure Across Immune Challenge Severities In A Lizard: Consequences For Innate Immunity, Locomotor Performance And Oxidative Status, Susannah S. French, Spencer Hudson
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Reptiles, like other vertebrates, rely on immunity to defend themselves from infection. The energetic cost of an immune response is liable to scale with infection severity, prompting constraints on other selfmaintenance traits if immune prioritization exceeds energy budget. In this study, adult male side-blotched lizards (Uta stansburiana) were injected with saline (control) or high (20 μg g−1 body mass) or low (10 μg g−1 body mass) concentrations of lipopolysaccharide (LPS) to simulate bacterial infections of discrete severities. The costs and consequences of the immune response were assessed through comparisons of change in resting metabolic rate (RMR), energy metabolites (glucose, glycerol, …
Data From: Yellow Air Day Advisory Study, Arthur J. Caplan
Data From: Yellow Air Day Advisory Study, Arthur J. Caplan
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Using a dataset consisting of daily vehicle trips, PM2.5 concentrations, along with a host of climactic control variables, we test the hypothesis that “yellow air day” advisories provided by the Utah Division of Air Quality resulted in subsequent reductions in vehicle trips taken during northern Utah’s winter-inversion seasons in the early 2000s. Winter inversions occur in northern Utah when climactic conditions are such that PM2.5 concentrations (derived mainly from vehicle emissions) become trapped in the lower atmosphere, leading to unhealthy air quality (concentrations of at least 35 µg/m3) over a span of what are called “red air days”. When concentrations …
Data For Farmland Preservation Study, Arthur J. Caplan, Brent C. Chamberlain
Data For Farmland Preservation Study, Arthur J. Caplan, Brent C. Chamberlain
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This study fills a gap in cultural ecosystem service (CES) assessment of prime farmland located in peri-urban areas by presenting results from a choice experiment recently conducted in Utah’s Wasatch Front region. The choice experiment was designed to account for heterogeneous effects associated with a wide array of socio-demographic and attitudinal characteristics on household preferences for farmland preservation, including farmland used for the joint production of solar power and agricultural products. We apply a mixed-logit model to our data that controls for preference heterogeneity among Wasatch Front households along two dimensions – at the individual household level and according to …
Anthropogenic And Climatic Factors Interact To Influence Reproductive Timing And Effort, Susannah S. French, Geoffrey Smith
Anthropogenic And Climatic Factors Interact To Influence Reproductive Timing And Effort, Susannah S. French, Geoffrey Smith
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Reproduction, although absolutely essential to a species’ persistence, is in itself challenging. As anthropogenic change increasingly affects every landscape on Earth, it is critical to understand how specific pressures impact the reproductive efforts of individuals, which directly contribute to the success or failure of populations. However, organisms rarely encounter a single burden at a time, and the interactions of environmental challenges can have compounding effects. Disentangling environmental and physiological pressures is difficult because they are often context-dependent and not generalizable, but long-term monitoring across variable landscapes and weather patterns can improve our understanding of these complex interactions. We tested the …
Data From: Recovery From Discrete Wound Severities In Side-Blotched Lizards (Uta Stansburiana): Implications For Energy Budget, Locomotor Performance, And Oxidative Stress, Susannah S. French, Spencer B. Hudson
Data From: Recovery From Discrete Wound Severities In Side-Blotched Lizards (Uta Stansburiana): Implications For Energy Budget, Locomotor Performance, And Oxidative Stress, Susannah S. French, Spencer B. Hudson
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Wounding events (predation attempts, competitive combat) result in injuries and/or infections that induce integrated immune responses for the recovery process. Despite the survival benefits of immunity in this context, the costs incurred may require investment to be diverted from traits contributing to immediate and/or future survival, such as locomotor performance and oxidative status. Yet, whether trait constraints manifest likely depends on wound severity and the implications for energy budget. For this study, food intake, body mass, sprint speed, and oxidative indices (reactive oxygen metabolites, antioxidant capacity) were monitored in male side-blotched lizards (Uta stansburiana) healing from cutaneous wounds of discrete …
Data For "Arch_Covid_Crowding_Vc", Wayne Freimund, Zachary D. Miller
Data For "Arch_Covid_Crowding_Vc", Wayne Freimund, Zachary D. Miller
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Monitoring of visitor use in Arches National Park to assess social distancing behaviors of visitors during the COVID-19 pandemic.