Biomedical Engineering and Bioengineering Commons^™

The Effects Of Organ-Based Tube Current Modulation On Radiation Dose And Image Quality In Computed Tomography Imaging, Diksha Gandhi

Master's Theses (2009 -)

The purpose of this thesis was to quantify dose and noise performance of organ-dose-based tube current modulation (ODM) through experimental studies with an anthropomorphic phantom and simulations with a voxelized phantom library. Tube current modulation is a dose reduction technique that modulates radiation dose in angular and/or slice directions based on patient attenuation. ODM technique proposed by GE Healthcare further reduces tube current for anterior source positions, without increasing current for posterior positions. Axial CT scans at 120 kV were performed on head and chest phantoms (Rando Alderson Research Laboratories, Stanford, CA) on an ODM-equipped scanner (Optima CT660, GE Healthcare, …

Reducing The Radiation Dose To Women Receiving Cardiac Ct Scans, Michael Hoppe

Master's Theses (2009 -)

This thesis aims to quantify the reduction in radiation dose deposited in glandular breast tissue achieved by using tilted gantry acquisition during cardiac CT scans. Previous work by Halpern et al. suggested using tilted acquisition parallel to the long axis of the patient’s heart. However, for a larger portion of the population this is not feasible due to the design of current scanners (which are limited to maximum tilt angles of 30 degrees). This study investigated the potential dose reduction and image quality effects at commercially available tilt angles between 0-30 degrees through simulation and experimental studies.

Upon IRB approval, …

A Non-Rigid Registration Method For Analyzing Myocardial Wall Motion For Cardiac Ct Images, Elizabeth B. Philps

Master's Theses (2009 -)

Cardiac resynchronization therapy (CRT) has a high percentage of non-responders. Successfully locating the optimal location for CRT lead placement on a priori images can increase efficiency in procedural preparation and execution and could potentially increase the rate of CRT responders.

Registration has been used in the past to assess the motion of medical images. Specifically, one method of non-rigid registration has been utilized to assess the motion of left ventricular MR cardiac images. As CT imaging is often performed as part of resynchronization treatment planning and is a fast and accessible means of imaging, extending this registration method to assessing …