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Biomedical Engineering and Bioengineering Commons

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Full-Text Articles in Biomedical Engineering and Bioengineering

Kinematic Analysis Of The Glenohumeral Joint: A Comparison Of Post-Operative Rotator Cuff Repair Patients And Controls, Ryan Richard Inawat Oct 2014

Kinematic Analysis Of The Glenohumeral Joint: A Comparison Of Post-Operative Rotator Cuff Repair Patients And Controls, Ryan Richard Inawat

Master's Theses (2009 -)

Rotator cuff (RC) repair is a standard surgical intervention used to alleviate pain and loss of function in the shoulder due to torn RC tendons, involving re-attachment of the tendon to the humerus. Quantitative evaluation of kinematics following RC repair is possible with video motion analysis techniques, yet is rarely performed. With the purpose of quantifying the effects of RC repair, a Vicon 524 (Oxford, UK) motion analysis system was used to investigate three-dimensional (3D) kinematics of the glenohumeral (GH) joint and thorax following supraspinatus repair. A validated, 18 marker, inverse dynamics model based on ISB standards was applied to …


Automated Selection Of The Optimal Cardiac Phase For Single-Beat Coronary Ct Angiography Reconstruction, Daniel Stassi Jul 2014

Automated Selection Of The Optimal Cardiac Phase For Single-Beat Coronary Ct Angiography Reconstruction, Daniel Stassi

Master's Theses (2009 -)

This thesis investigates an automated algorithm for selecting the optimal cardiac phase for CCTA reconstruction. Reconstructing a low-motion cardiac phase improves coronary artery visualization in coronary CT angiography (CCTA) exams. Currently, standard end-systole and/or mid-diastole default phases are prescribed or alternatively, quiescent phases are determined by the user. As manual selection may be time-consuming and standard locations may be suboptimal due to patient variability, an automated method is investigated. An automated algorithm was developed to select the optimal phase based on quantitative image quality (IQ) metrics. For each reconstructed slice at each reconstructed phase, an image quality metric was calculated …


The Effects Of Organ-Based Tube Current Modulation On Radiation Dose And Image Quality In Computed Tomography Imaging, Diksha Gandhi Jul 2014

The Effects Of Organ-Based Tube Current Modulation On Radiation Dose And Image Quality In Computed Tomography Imaging, Diksha Gandhi

Master's Theses (2009 -)

The purpose of this thesis was to quantify dose and noise performance of organ-dose-based tube current modulation (ODM) through experimental studies with an anthropomorphic phantom and simulations with a voxelized phantom library. Tube current modulation is a dose reduction technique that modulates radiation dose in angular and/or slice directions based on patient attenuation. ODM technique proposed by GE Healthcare further reduces tube current for anterior source positions, without increasing current for posterior positions. Axial CT scans at 120 kV were performed on head and chest phantoms (Rando Alderson Research Laboratories, Stanford, CA) on an ODM-equipped scanner (Optima CT660, GE Healthcare, …


Markerless Analysis Of Upper Extremity Kinematics During Standardized Pediatric Assessment, Jacob R. Rammer Apr 2014

Markerless Analysis Of Upper Extremity Kinematics During Standardized Pediatric Assessment, Jacob R. Rammer

Master's Theses (2009 -)

Children with hemiplegic cerebral palsy experience reduced motor performance in the affected upper extremity and are typically evaluated based on degree of functional impairment using activity-based assessments such as the Shriners Hospitals for Children Upper Extremity Evaluation (SHUEE), a validated clinical measure, to describe performance prior to and following rehabilitative or surgical interventions. Evaluations rely on subjective therapist scoring techniques and lack sensitivity to detect change. Objective clinical motion analysis systems are an available but time-consuming and cost-intensive alternative, requiring uncomfortable application of markers to the patient. There is currently no available markerless, low-cost system that quantitatively assesses upper extremity …


Computational Evaluation Of Shear Stress And Restenosis In Stented Coronary Arteries Using Optical Coherence Tomography, Joshua K. Hughey Apr 2014

Computational Evaluation Of Shear Stress And Restenosis In Stented Coronary Arteries Using Optical Coherence Tomography, Joshua K. Hughey

Master's Theses (2009 -)

The cause of coronary artery neointimal thickness (NT) leading to restenosis in ~10% of drug-eluting stents (DES) is unknown, but adverse wall shear stress (WSS) may contribute. Prior studies comparing WSS to restenosis for first generation DES yielded conflicting results, and cited different mechanisms of action for DES agents. Studies to date have not accounted for stent geometry, which dictates local WSS patterns influencing drug concentration. The objective of this investigation was to evaluate current generation stent platforms via their WSS patterns and their respective impact on NT. We prospectively enrolled 19 patients, who were randomized to thin-strut (81μm) 2-link …