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Full-Text Articles in Engineering

Hard, Soft And Off-The-Shelf Foot Orthoses And Their Effect On The Angle Of The Medial Longitudinal Arch: A Biplane Fluoroscopy Study, Megan E.R. Balsdon, Colin E. Dombroski, Kristen Bushey, Thomas Jenkyn Feb 2019

Hard, Soft And Off-The-Shelf Foot Orthoses And Their Effect On The Angle Of The Medial Longitudinal Arch: A Biplane Fluoroscopy Study, Megan E.R. Balsdon, Colin E. Dombroski, Kristen Bushey, Thomas Jenkyn

Mechanical and Materials Engineering Publications

Background: Foot orthoses have proven to be effective for conservative management of various pathologies. Pathologies of the lower limb can be caused by abnormal biomechanics such as abnormal foot structure and alignment, leading to inadequate support. Objectives: To compare biomechanical effects of different foot orthoses on the medial longitudinal arch (MLA) during dynamic gait using skeletal kinematics. Study Design: Prospective, cross-sectional study design. Methods: The MLA angle was measured for 12 participants among three groups: pes planus, pes cavus and normal arch. Five conditions were compared: three orthotic devices (hard custom foot orthosis (CFO), soft CFO, and off-the-shelf Barefoot Science©), …


Dynamic Light Scattering Optical Coherence Tomography To Probe Motion Of Subcellular Scatterers., Nico J J Arezza, Marjan Razani, Michael C Kolios Feb 2019

Dynamic Light Scattering Optical Coherence Tomography To Probe Motion Of Subcellular Scatterers., Nico J J Arezza, Marjan Razani, Michael C Kolios

Medical Biophysics Publications

Optical coherence tomography (OCT) is used to provide anatomical information of biological systems but can also provide functional information by characterizing the motion of intracellular structures. Dynamic light scattering OCT was performed on intact, control MCF-7 breast cancer cells and cells either treated with paclitaxel to induce apoptosis or deprived of nutrients to induce oncosis. Autocorrelations (ACs) of the temporal fluctuations of OCT intensity signals demonstrate a significant decrease in decorrelation time after 24 h in both the paclitaxel-treated and nutrient-deprived cell groups but no significant differences between the two groups. The acquired ACs were then used as input for …