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Full-Text Articles in Engineering

Molecular Modeling Of Tethered Polyelectrolytes For Novel Biomedical Applications, Merina Jahan Oct 2019

Molecular Modeling Of Tethered Polyelectrolytes For Novel Biomedical Applications, Merina Jahan

Theses and Dissertations

Current research trends throughout the world focus on designing intelligent materi- als and systems for diverse applications in all courses of life. Biomaterials research encompasses a major part in this revolution due to the increased effort in fulfilling unmet medical needs to treat complex physiological and neurodegenerative disorders. Polymers play inevitable roles in these research endeavors for their ubiquitous pres- ence in biological systems. Therefore, it is crucial to understand how the polymeric molecules interact within diverse biological environments, to efficiently engineer them for various drug delivery and biosensing systems. The use of experimental design and selection of different polymers …


Modeling Neutron Interaction Inside A 2d Reactor Using Monte Carlo Method, A. S. M. Fakhrul Islam Oct 2019

Modeling Neutron Interaction Inside A 2d Reactor Using Monte Carlo Method, A. S. M. Fakhrul Islam

Theses and Dissertations

Scientists and engineers have been working for many years to develop accurate approaches to analyzing nuclear power reactors using computer codes that closely model the behavior of neutrons in a reactor core. The Monte Carlo simulation method is capable of treating complex geometries with a high level of resolution and fidelity to model neutron interactions inside a reactor core. With the requirement of accurate modeling in reactor physics and dynamics and great innovation of computer technology, Monte Carlo method is becoming an ever more powerful tool and receiving rising attention. In this study, Monte Carlo method is used to model …


Three-Dimensional Collagen Tubes For In Vitro Modeling, Rebecca Jones Apr 2019

Three-Dimensional Collagen Tubes For In Vitro Modeling, Rebecca Jones

Theses and Dissertations

Collagen type I represents a novel material for three-dimensional in vitro models. While two-dimensional models are typically inadequate for recreating the complex processes of the body, collagen provides a three-dimensional basis with a variety of applications, including remodeling of vascular cells under tension and vascular stenosis. Smooth muscle cells reorganize and reconstruct their environment differently under conditions of tensions, such as with sutures, or under conditions without applied external tension. Vascular stenosis, the abnormal narrowing of blood vessels, arises from defective developmental processes or atherosclerosis-related adult pathologies. Stenosis triggers a series of adaptive cellular responses that induces adverse remodeling, which …