Engineering Commons^™

Computational Assessment Of Neural Probe And Brain Tissue Interface Under Transient Motion, Michael Polanco, Sebastian Bawab, Hangsoon Yoon

Mechanical & Aerospace Engineering Faculty Publications

The functional longevity of a neural probe is dependent upon its ability to minimize injury risk during the insertion and recording period in vivo, which could be related to motion-related strain between the probe and surrounding tissue. A series of finite element analyses was conducted to study the extent of the strain induced within the brain in an area around a neural probe. This study focuses on the transient behavior of neural probe and brain tissue interface with a viscoelastic model. Different stages of the interface from initial insertion of neural probe to full bonding of the probe by astro-glial …

Design And Analysis Of Blast Induced Traumatic Brain Injury Mechanism Using A Surrogate Headform: Instrumentation And Outcomes, Eyitejumade A. Sogbesan

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

Brain injury cases in military personnel exposed to improvised explosive devices (IED) in combat have been on the rise. In Iraq and Afghanistan improved helmets and body armor are not enough protection against blast wave threats. The United States military are sponsoring researchers and scientists around the globe to find the associations between pressure waves and traumatic brain injury (TBI).

Lack of accurate data and blast wave exposure information in returning soldiers has slowed the innovation needed to effectively diagnose TBI and other related brain injury as a result of pressure waves. More detailed data will be required to gain …

Dynamic Response Of Brain Subjected To Blast Loadings: Influence Of Frequency Ranges, Mehdi S. Chafi, Shailesh G. Ganpule, Linxia Gu, Namas Chandra

Department of Mechanical and Materials Engineering: Faculty Publications

Blast wave induced a frequency spectrum and large deformation of the brain tissue. In this study, new material parameters for the brain material are determined from the experimental data pertaining to these large strain amplitudes and wide frequencies ranging (from 0.01 Hz to 10 MHz) using genetic algorithms. Both hyperelastic and viscoelastic behavior of the brain are implemented into 2D finite element models and the dynamic responses of brain are evaluated. The head, composed of triple layers of the skull, including two cortical layers and a middle dipole sponge-like layer, the dura, cerebrospinal fluid (CSF), the pia mater and the …