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Medicine and Health Sciences

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Brain

2020

Articles 1 - 2 of 2

Full-Text Articles in Engineering

The Clinical Utilities Of Multi-Pinhole Single Photon Emission Computed Tomography, Ilker Ozsahin, Ling Chen, Arda Konik, Michael A. King, Freek J. Beekman, Greta S. P. Mok Oct 2020

The Clinical Utilities Of Multi-Pinhole Single Photon Emission Computed Tomography, Ilker Ozsahin, Ling Chen, Arda Konik, Michael A. King, Freek J. Beekman, Greta S. P. Mok

Open Access Publications by UMMS Authors

Single photon emission computed tomography (SPECT) is an important imaging modality for various applications in nuclear medicine. The use of multi-pinhole (MPH) collimators can provide superior resolution-sensitivity trade-off when imaging small field-of-view compared to conventional parallel-hole and fan-beam collimators. Besides the very successful application in small animal imaging, there has been a resurgence of the use of MPH collimators for clinical cardiac and brain studies, as well as other small field-of-view applications. This article reviews the basic principles of MPH collimators and introduces currently available and proposed clinical MPH SPECT systems.


A Neurovascular High-Frequency Optical Coherence Tomography System Enables In Situ Cerebrovascular Volumetric Microscopy, Giovanni J. Ughi, Miklos G. Marosfoi, Robert M. King, Jildaz Caroff, Lindsy M. Peterson, Benjamin H. Duncan, Erin T. Langan, Amanda J. Collins, Anita M. Leporati, Serge Rousselle, Demetrius K. Lopes, Matthew J. Gounis, Ajit S. Puri Jul 2020

A Neurovascular High-Frequency Optical Coherence Tomography System Enables In Situ Cerebrovascular Volumetric Microscopy, Giovanni J. Ughi, Miklos G. Marosfoi, Robert M. King, Jildaz Caroff, Lindsy M. Peterson, Benjamin H. Duncan, Erin T. Langan, Amanda J. Collins, Anita M. Leporati, Serge Rousselle, Demetrius K. Lopes, Matthew J. Gounis, Ajit S. Puri

Radiology Publications

Intravascular imaging has emerged as a valuable tool for the treatment of coronary and peripheral artery disease; however, no solution is available for safe and reliable use in the tortuous vascular anatomy of the brain. Endovascular treatment of stroke is delivered under image guidance with insufficient resolution to adequately assess underlying arterial pathology and therapeutic devices. High-resolution imaging, enabling surgeons to visualize cerebral arteries' microstructure and micron-level features of neurovascular devices, would have a profound impact in the research, diagnosis, and treatment of cerebrovascular diseases. Here, we present a neurovascular high-frequency optical coherence tomography (HF-OCT) system, including an imaging console ...