Engineering Commons^™

Pathological Brain Detection By A Novel Image Feature—Fractional Fourier Entropy, Shuihua Wang, Yudong Zhang, Xiaojun Yang, Ping Sun, Zhengchao Dong, Aijun Lu, Ti-Fei Yuan

Publications and Research

Aim: To detect pathological brain conditions early is a core procedure for patients so as to have enough time for treatment. Traditional manual detection is either cumbersome, or expensive, or time-consuming. We aim to offer a system that can automatically identify pathological brain images in this paper.Method: We propose a novel image feature, viz., Fractional Fourier Entropy (FRFE), which is based on the combination of Fractional Fourier Transform(FRFT) and Shannon entropy. Afterwards, the Welch’s t-test (WTT) and Mahalanobis distance (MD) were harnessed to select distinguishing features. Finally, we introduced an advanced classifier: twin support vector machine (TSVM). Results: A 10 …

A Model Microfluidics-Based System For The Human And Mouse Retina., Shawn Mishra, Ankush Thakur, Stephen Redenti, Maribel Vazquez

Publications and Research

The application of microfluidics technologies to the study of retinal function and response holds great promise for development of new and improved treatments for patients with degenerative retinal diseases. Restoration of vision via retinal transplantation therapy has been severely limited by the low numbers of motile cells observed post transplantation. Using modern soft lithographic techniques, we have developed the μRetina, a novel and convenient biomimetic microfluidics device capable of examing the migratory behavior of retinal lineage cells within biomimetic geometries of the human and mouse retina. Coupled computer simulations and experimental validations were used to characterize and confirm the formation …

Evaluation Of Viirs Land Surface Temperature Using Crest-Safe Air, Snow Surface, And Soil Temperature Data, Carlos L. Pérez Díaz, Tarendra Lakhankar, Peter Romanov, Reza Khanbilvardi, Yunyue Yu

Publications and Research

In this study, the Visible Infrared Imager Radiometer Suite (VIIRS) Land Surface Temperature (LST) Environmental Data Record (EDR) was evaluated against snow surface (T-skin) and near-surface air temperature (T-air) ground observations recorded at the Cooperative Remote Sensing Science and Technology Center—Snow Analysis and Field Experiment (CREST-SAFE), located in Caribou, ME, USA during the winters of 2013 and 2014. The satellite LST corroboration of snow-covered areas is imperative because high-latitude regions are often physically inaccessible and there is a need to complement the data from the existing meteorological station networks. T-skin is not a standard meteorological parameter commonly observed at synoptic …

Egf As A New Therapeutic Target For Medulloblastoma Metastasis, Jennifer Rico-Varela, Tanya Singh, Sean Mccutcheon, Maribel Vazquez

Publications and Research

Medulloblastoma (MB) is a malignant pediatric brain tumor known for its aggressive metastatic potential. Despite the well-documented migration of MB cells to other parts of the brain and spinal column, MB chemotaxis is poorly understood. Herein, we examined the in vitro migratory and cellular responses of MB-derived cells to external signaling of Epidermal Growth Factor (EGF), hepatocyte growth factor (HGF), platelet-derived growth factor (PDGF-BB), and the stromal cellderived factors 1-alpha (SDF-1). Experiments utilized transwell assays and immunocytochemistry to identify receptor activation in MB migration, and used a microfluidic platform to examine directionality, trajectory, and gradient-dependence of motile cells. Data illustrates …

Biomechanical Performances Of Networked Polyethylene Glycol Diacrylate: Effect Of Photoinitiator Concentration, Temperature, And Incubation Time, Morshed Khandaker, Albert Orock, Stefano Tarantini, Jeremiah White, Ozlem Yasar

Publications and Research

Nutrient conduit networks can be introduced within the Polyethylene Glycol Diacrylate (PEGDA) tissue construct to enable cells to survive in the scaffold. Nutrient conduit networks can be created on PEGDA by macrochannel to nanochannel fabrication techniques. Such networks can influence the mechanical and cell activities of PEGDA scaffold. There is no study conducted to evaluate the effect of nutrient conduit networks on the maximum tensile stress and cell activities of the tissue scaffold.The study aimed to explore the influence of the network architecture on the maximum tensile stress of PEGDA scaffold and compared with the nonnetworked PEGDA scaffold. Our study …

Evaluation Of The Snow Thermal Model (Sntherm) Through Continuous In Situ Observations Of Snow’S Physical Properties At The Crest-Safe Field Experiment, José Alberto Infante Corona, Jonathan Muñoz, Tarendra Lakhankar, Peter Romanov, Reza Khanbilvardi

Publications and Research

Snowpack properties like temperature or density are the result of a complex energy and mass balance process in the snowpack that varies temporally and spatially. The Snow Thermal Model (SNTHERM) is a 1-dimensional model, energy and mass balance-driven, that simulates these properties. This article analyzes the simulated snowpack properties using SNTHERM forced with two datasets, namely measured meteorological data at the Cooperative Remote Sensing Science and Technology-Snow Analysis and Field Experiment (CREST-SAFE) site and the National Land Data Assimilation System (NLDAS). The study area is located on the premises of Caribou Municipal Airport at Caribou (ME, USA). The model evaluation …

Molecular Helices As Electron Acceptors In High-Performance Bulk Heterojunction Solar Cells, Yu Zhong, M. Tuan Trinh, Rongsheng Chen, Geoffrey E. Purdum, Petr P. Khlyabich, Melda Sezen, Seokjoon Oh, Haiming Zhu, Brandon Fowler, Boyuan Zhang, Wei Wang, Chang-Yong Nam, Matthew Y. Sfeir, Charles T. Black, Michael L. Steigerwald, Yueh-Lin Loo, Fay Ng, X.-Y. Zhu, Colin Nuckolls

Publications and Research

Despite numerous organic semiconducting materials synthesized for organic photovoltaics in the past decade, fullerenes are widely used as electron acceptors in highly efficient bulk-heterojunction solar cells. None of the non-fullerene bulk heterojunction solar cells have achieved efficiencies as high as fullerene-based solar cells. Design principles for fullerene-free acceptors remain unclear in the field. Here we report examples of helical molecular semiconductors as electron acceptors that are on par with fullerene derivatives in efficient solar cells. We achieved an 8.3% power conversion efficiency in a solar cell, which is a record high for non-fullerene bulk heterojunctions. Femtosecond transient absorption spectroscopy revealed …

Carboxymethylcellulose Hydrogels Support Cns-Derived Tumor Cell Chemotactic Migration, Tanya Singh, Chandrasekhar Kothapalli, Devika Verma, Steven Nicoll, Maribel Vazquez

Publications and Research

The local microenvironment plays an important role in maintaining the dynamics of the extracellular matrix (ECM) and the cell-ECM relationship. ECM is a complex network of molecules with distinct mechanical and biochemical characteristics. When the mechanisms that are in place to maintain ECM homeostasis are deregulated, most likely, this is the onset of cancer. The ECM becomes highly disorganized and the cell-matrix relationship changes, thus promoting alternations in cell mechanisms and metastasis. Medulloblastoma (MB) is one of the most common, malignant pediatric brain tumors in the United States. In order to gain a better understanding between the cell-ECM relationship and …

Monitoring The Progression Of Spontaneous Articular Cartilage Healing With Infrared Spectroscopy, Megan P. O'Brien, Madhuri Penmatsa, Uday Palukuru, Paul West, Xu Yang, Mathias P. G. Bostrom, Theresa Freeman, Nancy Pleshko

Publications and Research

Objective. Evaluation of early compositional changes in healing articular cartilage is critical for understanding tissue repair and for therapeutic decision-making. Fourier transform infrared imaging spectroscopy (FT-IRIS) can be used to assess the molecular composition of harvested repair tissue. Furthermore, use of an infrared fiber-optic probe (IFOP) has the potential for translation to a clinical setting to provide molecular information in situ. In the current study, we determined the feasibility of IFOP assessment of cartilage repair tissue in a rabbit model, and assessed correlations with gold-standard histology.

Design. Bilateral osteochondral defects were generated in mature white New Zealand rabbits, and …

Sacrificial Amphiphiles: Eco-Friendly Chemical Herders As Oil Spill Mitigation Chemicals, Deeksha Gupta, Bivas Sarker, Keith Thadikaran, Vijay John, Charles Maldarelli, George John

Publications and Research

Crude oil spills are a major threat to marine biota and the environment. When light crude oil spills on water, it forms a thin layer that is difficult to clean by any methods of oil spill response. Under these circumstances, a special type of amphiphile termed as “chemical herder” is sprayed onto the water surrounding the spilled oil. The amphiphile forms a monomolecular layer on the water surface, reducing the air–sea surface tension and causing the oil slick to retract into a thick mass that can be burnt in situ. The current best-known chemical herders are chemically stable and nonbiodegradable, …

Mapping Regional Inundation With Spaceborne L-Band Sar, Bruce Chapman, Kyle Macdonald, Masanobu Shimada, Ake Rosenqvist, Ronny Schroeder, Laura Hess

Publications and Research

Shortly after the launch of ALOS PALSAR L-band SAR by the Japan Space Exploration Agency (JAXA), a program to develop an Earth Science Data Record (ESDR) for inundated wetlands was funded by NASA. Using established methodologies, extensive multi-temporal L-band ALOS ScanSAR data acquired bi-monthly by the PALSAR instrument onboard ALOS were used to classify the inundation state for South America for delivery as a component of this Inundated Wetlands ESDR (IW-ESDR) and in collaboration with JAXA’s ALOS Kyoto and Carbon Initiative science programme. We describe these methodologies and the final classification of the inundation state, then compared this with results …

Probabilistic Precipitation Estimation With A Satellite Product, Nir Y. Krakauer, Soni M. Pradhanang, Jeeban Panthi, Tarendra Lakhankar, Ajay K. Jha

Publications and Research

Satellite-based precipitation products have been shown to represent precipitation well over Nepal at monthly resolution, compared to ground-based stations. Here, we extend our analysis to the daily and subdaily timescales, which are relevant for mapping the hazards caused by storms as well as drought. We compared the Tropical Rainfall Measuring Mission (TRMM) Multi-satellite Precipitation Analysis (TMPA) 3B42RT product with individual stations and with the gridded APHRODITE product to evaluate its ability to retrieve different precipitation intensities. We find that 3B42RT, which is freely available in near real time, has reasonable correspondence with ground-based precipitation products on a daily timescale; rank …

Structural Patterns At All Scales In A Nonmetallic Chiral Au_133(Sr)_52 Nanoparticle, Chenjie Zeng, Yuxiang Chen, Kristin Kirschbaum, Kannatassen Appavoo, Matthew Y. Sfeir, Rongchao Jin

Publications and Research

Structural ordering is widely present in molecules and materials. However, the organization of molecules on the curved surface of nanoparticles is still the least understood owing to the major limitations of the current surface characterization tools. By the merits of x-ray crystallography, we reveal the structural ordering at all scales in a super robust 133–gold atom nanoparticle protected by 52 thiolate ligands, which is manifested in self-assembled hierarchical patterns starting from the metal core to the interfacial –S–Au–S– ladder-like helical “stripes” and further to the “swirls” of carbon tails. These complex surface patterns have not been observed in the smaller …

National Livestock Policy Of Nepal: Needs And Opportunities, Upendra B. Pradhanang, Soni M. Pradhanang, Arhan Sthapit, Nir Y. Krakauer, Ajay K. Jha, Tarendra Lakhankar

Publications and Research

This paper describes Nepal’s national livestock policies and considers how they can be improved to help meet the pressing national challenges of economic development, equity, poverty alleviation, gender mainstreaming, inclusion of marginalized and underprivileged communities, and climate vulnerability. Nepal is in the process of transforming its government from a unitary system to a federal democratic structure through the new constitution expected by 2015, offering the opportunity to bring a new set of priorities and stakeholders to policymaking. Nepal’s livestock subsector comes most directly within the purview of the National Agricultural Policy 2004, Agro-Business Policy, 2006 and Agricultural Sectoral Operating Policies …

Spatial And Temporal Variability Of Rainfall In The Gandaki River Basin Of Nepal Himalaya, Jeeban Panthi, Piyush Dahal, Madan Lall Shrestha, Suman Aryal, Nir Y. Krakauer, Soni M. Pradhanang, Tarendra Lakhankar, Ajay K. Jha, Mohan Sharma, Ramchandra Karki

Publications and Research

Landslides, floods, and droughts are recurring natural disasters in Nepal related to too much or too little water. The summer monsoon contributes more than 80% of annual rainfall, and rainfall spatial and inter-annual variation is very high. The Gandaki River, one of the three major rivers of Nepal and one of the major tributaries of the Ganges River, covers all agro-ecological zones in the central part of Nepal. Time series tests were applied for different agro-ecological zones of the Gandaki River Basin (GRB) for rainfall trends of four seasons (pre-monsoon, monsoon, post-monsoon and winter) from 1981 to 2012. The non-parametric …

Solar And Conservative Energy, Md Zahidur Rahman, Jonathan Anspike

Publications and Research

In the solar power and conservative energy, our basic mission was to build things that don’t use any sort of fuel that harms the environment. One of the most well-liked ways of conserving energy is using solar panels. Solar panels capture light, and transforms that light into electrical. The first objective in this research was to build an electric car that uses solar panels. To do so we connected a solar panel to a motor which rotates a series of gears that turns the wheels. We used a lot of sunlight though to power the motor enough were the gears …

Urban And Rural Msw Stream Characterization For Separate Collection Improvement, Simona Ciuta, Tiberiu Apostol, Valentin Rusu

Publications and Research

In the new legislation framework enacted by new member countries of the European Union (EU), the characterization of municipal solid waste (MSW) represents an important instrument for local governments and sanitation operators in setting and achieving targets for waste recycling and recovery. This paper presents the results of a study conducted in accordance with the Romanian methodology for domestic wastes characterization ROMECOM, aiming to provide a proper basis for developing clear and realistic forecasts in current municipal waste management, based on MSW composition and generation rate. The analyzed MSW came both from areas where the waste is collected in mixed …

Contact Analysis For Coupling Of Plates And Screws In Fracture Fixation Of Cortical Bone, Gaffar Gailani, Rachid Moumni, Malek Brahimi

Publications and Research

Internal fixation is a common treatment for bone fracture. Bone fracture occurs due to different reasons such as motor vehicle accidents, falling,…etc. The treatment is performed by fixing plate and screws to the fracture site. Lack of stability of the implants (plates and screws) may lead to delay in healing or failure of treatment. Micro-motion between the implant and the bone may cause formation of fibrous tissue around the screw which will lead to implant loosening. On the other hands, firm fixing of the conventional implants (Dynamic Compression Plates) may lead to delay resorption and delay in healing. Recently, Locked …

Capstone Interdisciplinary Team Project: A Requirement For The Ms In Sustainability Degree, Latif M. Jiji, Irvin Sam Schonfeld, George A. Smith

Publications and Research

Purpose – This paper aims to describe experience gained with a required six-credit year-long course, the Capstone Interdisciplinary Team Project, a key component of the Master of Science (MS) in Sustainability degree at the City College of New York. A common feature of sustainability problems is their interdisciplinary nature. Solutions to sustainability problems often require professionals with different training and backgrounds to work as a team. A sustainability curriculum should provide students with the skills needed to competently participate in an interdisciplinary team.

Design/methodology/approach – Instructors drawn from different departments and divisions of the college developed a pool of sustainability-focused …

Coalescence-Induced Jumping Of Droplet: Inertia And Viscosity Effects, Samaneh Farokhirad, Jeffrey F. Morris, Taehun Lee

Publications and Research

The problem of coalescence-induced self-propelled jumping of droplet is studied using three-dimensional numerical simulation. The focus is on the effect of inertia and in particular the effect of air density on the behavior of the merged droplet during jumping. A lattice Boltzmann method is used for two identical, static micro-droplets coalescing on a homogeneous substrate with contact angle ranging from 0◦ to 180◦. The results reveal that the effect of air density is significant on detachment of the merged droplet from the substrate at the later stage of the jumping process; the larger the air density, the larger the jumping …

Framing The Question, "Who Governs The Internet?", Robert J. Domanski

Publications and Research

There remains a widespread perception among both the public and elements of academia that the Internet is “ungovernable”. However, this idea, as well as the notion that the Internet has become some type of cyber-libertarian utopia, is wholly inaccurate. Governments may certainly encounter tremendous difficulty in attempting to regulate the Internet, but numerous types of authority have nevertheless become pervasive. So who, then, governs the Internet? This book will contend that the Internet is, in fact, being governed, that it is being governed by specific and identifiable networks of policy actors, and that an argument can be made as to …

Mobile Apps In Collection Development: Supporting A Mobile Learning Environment, Stefanie Havelka, Rebecca Arzola

Publications and Research

We will discuss our rationale and thoughts on why we believe mobile apps should be part of a library’s collection development policy. An updated policy with apps encourages a mobile learning environment that is technologically diverse while being holistically supportive of its users and research.