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Development Of A Comsol Microdialysis Model, Towards Creation Of Microdialysis On A Chip With Improved Geometries And Recovery, Patrick Pysz
Development Of A Comsol Microdialysis Model, Towards Creation Of Microdialysis On A Chip With Improved Geometries And Recovery, Patrick Pysz
Graduate Theses and Dissertations
Microdialysis (µD) sampling is a diffusion-limited sampling method that has been widely used in different biomedical fields for greater than 35 years. Device calibration for in vivo studies is difficult for current non-steady state analytes of interest correlated with both inflammatory response and microbial signaling molecules (QS); which exist in low ng/mL to pg/mL with molecular weights over a wide range of 170 Da to 70 kDa. The primary performance metric, relative recovery (RR), relating the collected sample to the extracellular space concentration varies from 10% to 60% per analyte even under controlled bench-top conditions. Innovations in microdialysis device design …
Optimization Of Miniaturized Resonant Microwave Cavities For Use In Q-Thrusters, Joshua Steven Pennington
Optimization Of Miniaturized Resonant Microwave Cavities For Use In Q-Thrusters, Joshua Steven Pennington
Graduate Theses and Dissertations
A gedankenexperiment was considered to compare a hypothetical thruster that used no reaction mass to propulsion methods currently in use. A brief discussion of previous research work done on closed resonant cavity thrust devices was conducted. Using the previous work as a template, a simulation plan was devised. Computational models of resonant microwave cavities were constructed and investigated using COMSOL software. These COMSOL simulations were verified against known analytical solutions using Matlab software as a computational tool. Multiphysics simulations were created to study the microwave heating environment of the resonant cavities. From the COMSOL study outputs, the electromagnetic field magnitude, …