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Botox Onabotulinumtoxina: Meta-Analysis Of The Severity Of Off-Label Botox Use In Children With Cerebral Palsy, Erica A. Morris
Botox Onabotulinumtoxina: Meta-Analysis Of The Severity Of Off-Label Botox Use In Children With Cerebral Palsy, Erica A. Morris
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Abstract
The brand name Botox was first assigned to a batch of botulinum toxin serotype A by Stanley Fahn, internationally avowed Doctor of Medicine and member of the Psychopharmacology Advisory Committee for the Food and Drug Administration (Erbguth, 2009; Fahn, 2016). Botulinum toxin is classified as one of the most potent toxic substances in the world. Efficacy for the therapeutic use of botulinum toxin is based upon the premise that botulinum toxin remains in the peripheral nervous system and is incapable of breaching the Blood-Brain Barrier (Tenenbaum, 2016). Since receiving initial approval in 1989 botulinum toxin serotype A now also …